The Candidate is a Psychologist and a new Assistant Professor in the Department of Epidemiology and Public Health at the Yale University School of Medicine. Her long-term career objective is to establish an independent program of research in the area of psychosocial epidemiology, with an emphasis on cardiovascular disease (CVD) in African-American women. The integrated research and training program described in this application extends her prior work in Psychology and African-American women's health, and incorporates new training in: 1) Epidemiology and Biostatistics;2) Cardiovascular Physiology;3) Study design and implementation;and 4) State-of-the-art Psychological Assessment techniques. The research proposed in this Mentored Scientist Career Development Award utilizes a multi-method approach to determine whether self-reported experiences of "everyday" discrimination are significantly associated with indices of CVD in two separate cohorts of African-American women. The research plan describes three separate but interrelated projects designed to examine the proposed everyday discrimination and CVD association. Methodologies employed include: Secondary data analysis, primary data collection, and Ecological Momentary Assessment. The proposed career development plan will develop and enhance the Candidate's knowledge base, skills, and expertise, and findings from the proposed studies will lay the foundation for a program of research examining the psychosocial predictors of poor CVD outcomes in African-American women. Important advancements in the proposed research are the rigorous application of psychosocial constructs to the study of patterns of disease, and the specific evaluation of the impact of a common psychsocial stressor (i.e., "everyday" discrimination) that is understudied in terms of its public health impact.

National Institute of Health (NIH)
Research Scientist Development Award - Research & Training (K01)
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Study Section
Special Emphasis Panel (ZHL1)
Program Officer
Kaufmann, Peter G
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Yale University
Public Health & Prev Medicine
Schools of Medicine
New Haven
United States
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Lewis, Tené T; Williams, David R; Tamene, Mahader et al. (2014) Self-Reported Experiences of Discrimination and Cardiovascular Disease. Curr Cardiovasc Risk Rep 8:365
Henderson, Kimberly M; Clark, Cari J; Lewis, Tené T et al. (2013) Psychosocial distress and stroke risk in older adults. Stroke 44:367-72
Lewis, Tene T; Troxel, Wendy M; Kravitz, Howard M et al. (2013) Chronic exposure to everyday discrimination and sleep in a multiethnic sample of middle-aged women. Health Psychol 32:810-9
Slopen, Natalie; Dutra, Lauren M; Williams, David R et al. (2012) Psychosocial stressors and cigarette smoking among African American adults in midlife. Nicotine Tob Res 14:1161-9
Hickson, DeMarc A; Lewis, Tene T; Liu, Jiankang et al. (2012) The associations of multiple dimensions of discrimination and abdominal fat in African American adults: the Jackson Heart Study. Ann Behav Med 43:4-14
Lewis, Tene T; Yang, Frances M; Jacobs, Elizabeth A et al. (2012) Racial/ethnic differences in responses to the everyday discrimination scale: a differential item functioning analysis. Am J Epidemiol 175:391-401
Lewis, Tene T; Guo, Hongfei; Lunos, Scott et al. (2011) Depressive symptoms and cardiovascular mortality in older black and white adults: evidence for a differential association by race. Circ Cardiovasc Qual Outcomes 4:293-9
Lewis, Tene T; Kravitz, Howard M; Janssen, Imke et al. (2011) Self-reported experiences of discrimination and visceral fat in middle-aged African-American and Caucasian women. Am J Epidemiol 173:1223-31
Lewis, Tene T; Kravitz, Howard M; Powell, Lynda H (2011) Response to invited commentary. Three of the authors respond to "Discrimination and cardiovascular disease". Am J Epidemiol 173:1244-5
Lewis, Tené T; Sutton-Tyrrell, Kim; Penninx, Brenda W et al. (2010) Race, psychosocial factors, and aortic pulse wave velocity: the Health, Aging, and Body Composition Study. J Gerontol A Biol Sci Med Sci 65:1079-85

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