Through this research career development award, I will complete the initial steps to establish myself as an independent researcher in HIV/AIDS behavioral research to reduce health disparities in Latino communities infected with HIV. Using didactic and mentored learning, I will improve upon my existing behavioral, qualitative, and quantitative research skills to address the issue of low participation in HIV/AIDS clinical trials in Latino communities. Proportionate representation of minority populations in research trials is necessary to improve research capacity to generalize results to diverse populations infected with HIV. My specific research aims are to: 1) Describe and understand the attitudes, beliefs, cultural and social norms, provider and system influences relating to entry into clinical trials in HIV+ Mexican-origin Latinos, and 2) Develop and pilot test an intervention for improving understanding and acceptance of HIV clinical trials participation by HIV+ Mexican-origin Latinos and their communities. The theoretical framework of the research plan is the Behavioral Model of Health Services Use (Andersen, Aday, et al.). The research plan will be carried out in three phases, each phase linked to a career development objective and activity. In Phase 1 I will conduct formative research using qualitative methods with HIV+ Mexican-origin Latinos, including design and implementation of an in-depth interview protocol and focus group questions to explore factors to consider in attempting to improve clinical trials participation in Latino populations. In Phase 2 I will carry out qualitative analysis, develop a social cognitive model of participation in research, develop research hypotheses, and develop and pilot test a survey to test the social cognitive model in HIV+ Mexican-origin Latinos. In Phase 3 I will validate the survey, analyze and report outcomes, design and pilot-test a behavioral intervention to increase clinical trials participation in HIV+ Mexican-origin Latinos, and finally, use intervention pilot data to prepare an R01 proposal to the NIH to promote participation of HIV+ Latinos in clinical trials.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Scientist Development Award - Research & Training (K01)
Project #
5K01MH072353-04
Application #
7407454
Study Section
Special Emphasis Panel (ZRG1-AARR-G (02))
Program Officer
Grossman, Cynthia I
Project Start
2005-05-25
Project End
2010-04-30
Budget Start
2008-05-01
Budget End
2009-04-30
Support Year
4
Fiscal Year
2008
Total Cost
$120,338
Indirect Cost
Name
University of California San Diego
Department
Pediatrics
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Muñoz, Fátima A; Servin, Argentina E; Garfein, Richard S et al. (2015) Deportation history among HIV-positive Latinos in two US-Mexico border communities. J Immigr Minor Health 17:104-11
Servin, Argentina E; Muñoz, Fátima A; Zúñiga, María Luisa (2014) Healthcare provider perspectives on barriers to HIV-care access and utilisation among Latinos living with HIV in the US-Mexico border. Cult Health Sex 16:587-99
Muñoz, Fátima A; Servin, Argentina E; Kozo, Justine et al. (2013) A binational comparison of HIV provider attitudes towards the use of complementary and alternative medicine among HIV-positive Latino patients receiving care in the US-Mexico border region. AIDS Care 25:990-7
Servin, Argentina E; Muñoz, Fátima A; Strathdee, Steffanie A et al. (2012) Choosing sides: HIV health care practices among shared populations of HIV-positive Latinos living near the US-Mexico border. J Int Assoc Physicians AIDS Care (Chic) 11:348-55
Zúñiga, María Luisa; Muñoz, Fátima; Kozo, Justine et al. (2012) A binational study of patient-initiated changes to antiretroviral therapy regimen among HIV-positive Latinos living in the Mexico-U.S. border region. AIDS Behav 16:1622-9
Pollini, Robin A; Blanco, Estela; Crump, Carol et al. (2011) A community-based study of barriers to HIV care initiation. AIDS Patient Care STDS 25:601-9
Zúñiga, María Luisa; Blanco, Estela; Brennan, Jesse J et al. (2011) Binational care-seeking behavior and health-related quality of life among HIV-infected Latinos in the U.S.-Mexico border region. J Assoc Nurses AIDS Care 22:162-72
Munoz, Fatima A; Pollini, Robin A; Zuniga, Maria Luisa et al. (2010) Condom access: Associations with consistent condom use among female sex workers in two northern border cities of Mexico. AIDS Educ Prev 22:455-65
Deiss, Robert; Garfein, Richard S; Lozada, Remedios et al. (2009) Influences of cross-border mobility on tuberculosis diagnoses and treatment interruption among injection drug users in Tijuana, Mexico. Am J Public Health 99:1491-5
Brouwer, K C; Lozada, R; Cornelius, W A et al. (2009) Deportation along the U.S.-Mexico border: its relation to drug use patterns and accessing care. J Immigr Minor Health 11:1-6

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