This K05 grant will provide training, educational, and research experiences that allow Dr. Timothy Baker to perform groundbreaking research, both transdisciplinary and translational, on tobacco use and other addictive disorders. Specifically, the research will foster the integration of theories, data, and methods from diverse disciplines and among many collaborators. In addition, it will permit him to conduct translational research in which innovative basic science models and methods are used to generate new treatments and assessments;viz. to facilitate the transfer of basic science findings and perspectives so that they achieve more effective real-world application. The requested support also will facilitate Dr. Baker's teaching and training of the future cadre of addiction scientists, especially physicians-in-training. To accomplish these aims, the applicant will: (1) use the requested support to reduce his administrative and teaching obligations;(2) take classes, engage in intensive reading and study, and consult with experts in targeted areas of special relevance to the applicant's research;(3) design and conduct new research studies that provide outstanding opportunity for transdisciplinary and translational research addressing tobacco use and other addictive disorders;and, (4) conduct on-going theory and methods training seminars and serve as a research mentor, with these efforts aimed especially at physicians-in-training. The proposed work will benefit from the tremendous resources available in the applicant's research environment and by his on-going research with a large transdisciplinary team. This K05 grant should benefit public health by enhancing the quality of research on addictive disorders performed by Dr. Baker, his collaborators, and those he trains. Specifically, this support should promote better understanding of tobacco use and other addictive disorders and, ultimately, impact the health of the nation by producing more effective treatments for these devastating, diseases.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Scientist Award (K05)
Project #
5K05CA139871-02
Application #
7689810
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Perkins, Susan N
Project Start
2008-09-19
Project End
2013-08-31
Budget Start
2009-09-01
Budget End
2010-08-31
Support Year
2
Fiscal Year
2009
Total Cost
$170,073
Indirect Cost
Name
University of Wisconsin Madison
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Schlam, Tanya R; Cook, Jessica W; Baker, Timothy B et al. (2018) Can we increase smokers' adherence to nicotine replacement therapy and does this help them quit? Psychopharmacology (Berl) 235:2065-2075
Teitelbaum, A M; Murphy, S E; Akk, G et al. (2018) Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain. Pharmacogenomics J 18:136-143
Mitchell, Carol; Piper, Megan E; Korcarz, Claudia E et al. (2018) Echogenicity of the carotid arterial wall in active smokers. J Diagn Med Sonogr 34:161-168
Baker, Timothy B; Smith, Stevens S; Bolt, Daniel M et al. (2017) Implementing Clinical Research Using Factorial Designs: A Primer. Behav Ther 48:567-580
Piper, Megan E; Cook, Jessica W; Schlam, Tanya R et al. (2017) Toward precision smoking cessation treatment II: Proximal effects of smoking cessation intervention components on putative mechanisms of action. Drug Alcohol Depend 171:50-58
Petersen, Angela; Mermelstein, Robin; Berg, Kristin M et al. (2017) Offering smoking treatment to primary care patients in two Wisconsin healthcare systems: Who chooses smoking reduction versus cessation? Prev Med 105:332-336
Cook, Jessica W; Baker, Timothy B; Beckham, Jean C et al. (2017) Smoking-induced affect modulation in nonwithdrawn smokers with posttraumatic stress disorder, depression, and in those with no psychiatric disorder. J Abnorm Psychol 126:184-198
Piper, Megan E; Schlam, Tanya R; Cook, Jessica W et al. (2017) Toward precision smoking cessation treatment I: Moderator results from a factorial experiment. Drug Alcohol Depend 171:59-65
King, Cecile C; Piper, Megan E; Gepner, Adam D et al. (2017) Longitudinal Impact of Smoking and Smoking Cessation on Inflammatory Markers of Cardiovascular Disease Risk. Arterioscler Thromb Vasc Biol 37:374-379
Chen, Li-Shiun; Baker, Timothy; Brownson, Ross C et al. (2017) Smoking Cessation and Electronic Cigarettes in Community Mental Health Centers: Patient and Provider Perspectives. Community Ment Health J 53:695-702

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