This application is a second resubmission for a K05 Senior Scientist Award as a competing continuation of K02 DA00139. To sustain my professional development, the specific aims of this K05 are to: (1) develop and apply advanced statistical methods to improve the knowledge of long-term patterns and consequences of drug use, treatment process and outcomes, and the interplay of drug use patterns with other service systems;(2) train and mentor students and junior investigators;(3) advise policymakers, service providers, and researchers on long-term patterns and consequences of drug use and treatment outcomes;and (4) consolidate and widely disseminate the knowledge and experiences accumulated throughout my research career via journal articles, books, and a web site. Building upon work accomplished during the past and current Research Career Award periods, I will continue pursuing my research goals by conducting 3 research projects: (1) a study of treatment system impacts and outcomes of California's Proposition 36 (providing drug treatment in lieu of incarceration);(2) a study on the access and outcomes associated with drug treatment and mental health services;and (3) a Center project to advance longitudinal drug abuse research, in which archival data from my previous studies will also be analyzed as issues are identified. A special emphasis is on the implications of research findings pertinent to the development of improved treatment strategies and on providing advice on social policy changes. I will continue to provide training and mentorship to students and junior investigators to assist their career advancement. My professional growth will involve continued development and application of innovative statistical methodologies in support of my substantive work. I will also expand my capacity to conduct interdisciplinary research by increasing my knowledge regarding other disciplines relevant to drug abuse research and through collaborative work. My affiliation with the Neuropsychiatric Institute (NPI) in the UCLA Department of Psychiatry and Biobehavioral Sciences provides the optimum setting for my career development. In this context, I will conduct research and will receive additional training in clinical aspects of drug abuse treatment and in the implementation of treatment services. Furthermore, my psychosocial research knowledge and skills in drug abuse issues will contribute to UCLA's general program in drug abuse research by complementing NPI's biobehavioral perspective.

National Institute of Health (NIH)
National Institute on Drug Abuse (NIDA)
Research Scientist Award (K05)
Project #
Application #
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Wiley, Tisha R A
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Project End
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Fiscal Year
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University of California Los Angeles
Schools of Medicine
Los Angeles
United States
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Hser, Yih-Ing; Saxon, Andrew J; Huang, David et al. (2014) Treatment retention among patients randomized to buprenorphine/naloxone compared to methadone in a multi-site trial. Addiction 109:79-87
Teruya, Cheryl; Schwartz, Robert P; Mitchell, Shannon Gwin et al. (2014) Patient perspectives on buprenorphine/naloxone: a qualitative study of retention during the starting treatment with agonist replacement therapies (START) study. J Psychoactive Drugs 46:412-26
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Hara, Motoaki; Huang, David Y C; Weiss, Robert E et al. (2013) Concurrent life-course trajectories of employment and marijuana-use: exploring interdependence of longitudinal outcomes. J Subst Abuse Treat 45:426-32
Hser, Yih-Ing; Fu, Liming; Wu, Fei et al. (2013) Pilot trial of a recovery management intervention for heroin addicts released from compulsory rehabilitation in China. J Subst Abuse Treat 44:78-83
Lanza, H Isabella; Huang, David Y C; Murphy, Debra A et al. (2013) A Latent Class Analysis of Maternal Responsiveness and Autonomy-Granting in Early Adolescence: Prediction to Later Adolescent Sexual Risk-Taking. J Early Adolesc 33:404-428
Evans, Elizabeth; Li, Libo; Grella, Christine et al. (2013) Developmental timing of first drug treatment and 10-year patterns of drug use. J Subst Abuse Treat 44:271-9
Evans, Elizabeth; Li, Libo; Pierce, Jennifer et al. (2013) Explaining long-term outcomes among drug dependent mothers treated in women-only versus mixed-gender programs. J Subst Abuse Treat 45:293-301

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