The institution is sponsoring a candidate with certification in internal medicine in preventive medicine, and epidemiology; the candidate also has an ongoing research program and has teaching experience in epidemology. The institutional objectives are to provide adequate scientific resources for the growing number of doctoral students in the Department of Epidemiology and Public Health having an interest in cancer, to foster collaborative interdisciplinary research, and to make specific improvements in the preventive oncology curriculum. The candidate's plan follows: Research by doctoral students will be supervised by the candidate, who has developed potential projects. These studies are presented to demonstrate ability to provide scientific resources. To deepen his knowledge of preventive oncology, to enrich the curriculum for students and to stimulate research, the candidate will undertake three reviews in a structured program of collaboration with an experienced pathologist and a clinical oncologist-laboratory scientist: (a) review of precursor lesions; and (b) reviews of dietary and genetic risk factors. The three reviews (precursor lesions, diet and genetics) will stimulate collaborative peer-reviewed research outside the Award and will also make a major contribution to teaching. The candidate, who will be assuming full responsibility for the public health course Epidemiology and Biostatistics of Cancer, will make several changes in the teaching as a result of this Award; introduction of a syllabus; greater emphasis on precursor lesions, dietary factors and genetic fators; and greater input from other faculty members having specialized expertise in other areas pertinent to preventive oncology. The award will also facilitate teaching by the candidate through occasional lectures in other courses and brief discussions in the setting of case presentations in clinical oncology and pathology. Measurable outcomes of the Award will be completion of research projects satisfying doctoral thesis requirements, journal publications, stimulation of peer-reviewed research supported outside the Award, and a unique syllabus in preventive oncology.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Academic/Teacher Award (ATA) (K07)
Project #
5K07CA000875-04
Application #
3076736
Study Section
(SRC)
Project Start
1983-08-01
Project End
1988-07-31
Budget Start
1986-08-01
Budget End
1987-07-31
Support Year
4
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Yale University
Department
Type
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Roush, G C; Schymura, M J; Holford, T R (1988) Patterns of invasive melanoma in the Connecticut Tumor Registry. Is the long-term increase real? Cancer 61:2586-95
Roush, G C; Nordlund, J J; Forget, B et al. (1988) Independence of dysplastic nevi from total nevi in determining risk for nonfamilial melanoma. Prev Med 17:273-9
Roush, G C; Schymura, M J; Stevenson, J M et al. (1987) Time and age trends for sinonasal cancer in Connecticut incidence and US mortality rates. Cancer 60:422-8
Roush, G C; Kirkwood, J M; Ernstoff, M et al. (1986) Reproducibility and validity in the clinical diagnosis of the nonfamilial dysplastic nevus: work in progress. Recent Results Cancer Res 102:154-8
Roush, G C; Barnhill, R L; Duray, P H et al. (1986) Diagnosis of the dysplastic nevus in different populations. J Am Acad Dermatol 14:419-25
Roush, G C; Schymura, M J; Holford, T R et al. (1985) Time period compared to birth cohort in Connecticut incidence rates for twenty-five malignant neoplasms. J Natl Cancer Inst 74:779-88
Roush, G C; Schymura, M J; Holford, T R (1985) Risk for cutaneous melanoma in recent Connecticut birth cohorts. Am J Public Health 75:679-82