The overall goal of the Clinical Oncology Research Career Development Program is to support the intent of the Paul Calabresi Award for Clinical Oncology (K12). The Program fosters interdisciplinary training in clinical and translational oncology therapeutic research for physicians in one of a number of oncology disciplines, including medical, surgical, dermatologic, pediatric, radiation and pathology. By designing a K12 program that brings together these broad disciplines, the Paul Calabresi Scholars themselves form a multidisciplinary group whose collaborations and interactions augment the overall training efforts under the K12 program. Firm core requirements include completion of required and elective course work for a Certificate in Clinical Translational Oncology at CWRU. A basic research effort is a required part of the training program and is linked to the clinical research efforts that include writing and activating a therapeutic clinical protocol and submission of a career development award application. These efforts will result in highly qualified Paul Calabresi scholars capable of independent research in clinical oncology and therapeutics with a team science orientation based in hypothesis testing of important translational questions in the field. The Program brings together strong Internal and External Advisory Committees committed and experienced in the area of clinical translational therapeutics research in oncology. The Program and the cancer center provides scholars with an outstanding environment to pursue career development. Past trainees have emerged as academic physicians developing independent clinical research programs often with external funding and with active investigator-initiated clinical trial efforts.

Public Health Relevance

This mentored career development program supports physician investigators to gain skills in cancer research and clinical therapeutics that emphasizes innovative treatments and use of genomics to select proper and individualized treatments for cancer patients, increasing the likelihood that such treatment will be effective.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
2K12CA076917-16
Application #
8486977
Study Section
Subcommittee G - Education (NCI)
Program Officer
Damico, Mark W
Project Start
1997-09-30
Project End
2018-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
16
Fiscal Year
2013
Total Cost
$721,474
Indirect Cost
$54,488
Name
Case Western Reserve University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Cummings 3rd, Kenneth C; Patel, Meatal; Htoo, Phyo Than et al. (2014) A comparison of the effects of epidural analgesia versus traditional pain management on outcomes after gastric cancer resection: a population-based study. Reg Anesth Pain Med 39:200-7
Raigani, Siavash; Hardacre, Jeffrey M; Kim, Julian et al. (2014) Trends in the surgical treatment of gastric adenocarcinoma. Ann Surg Oncol 21:569-74
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de Blank, Peter Matthew Kennedy; Berman, Jeffrey Ira; Liu, Grant T et al. (2013) Fractional anisotropy of the optic radiations is associated with visual acuity loss in optic pathway gliomas of neurofibromatosis type 1. Neuro Oncol 15:1088-95
Cummings, Linda C; Shah, Ninad; Maimone, Santo et al. (2013) Barrett's esophagus and the risk of obstructive sleep apnea: a case-control study. BMC Gastroenterol 13:82
Leidner, Rom S; Ravi, Lakshmeswari; Leahy, Patrick et al. (2012) The microRNAs, MiR-31 and MiR-375, as candidate markers in Barrett's esophageal carcinogenesis. Genes Chromosomes Cancer 51:473-9
Moinova, Helen; Leidner, Rom S; Ravi, Lakshmeswari et al. (2012) Aberrant vimentin methylation is characteristic of upper gastrointestinal pathologies. Cancer Epidemiol Biomarkers Prev 21:594-600
Cummings 3rd, Kenneth C; Xu, Fang; Cummings, Linda C et al. (2012) A comparison of epidural analgesia and traditional pain management effects on survival and cancer recurrence after colectomy: a population-based study. Anesthesiology 116:797-806

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