The principal mission of the University of California, San Francisco (UCSF) Women's Reproductive Health Research (WRHR) Career Development Center is to promote health and prevent disease in women by expanding the pool of well-trained, imaginative, productive investigators in the field of women's reproductive health. It is our purpose to recruit, mentor, and prepare outstanding candidates to acquire and refine the skills needed to reach this goal. As one of the original institutions awarded a WRHR Center, we have established an infrastructure, curriculum, and Scholar mentoring system to meet the challenge of training the next generation of academic Obstetrician-Gynecologists. Based on the successes of two cohorts of Scholars over the past 10 years, we propose a structured Scholar program of sufficient duration, relevant didactic education, and immersion into a vibrant, intellectually challenging, research community, leading to academic independence. The education of our Scholars will be further enriched by our collaboration with the UCSF Clinical &Translational Science Institute (CTSI), which provides ongoing infrastructure, resource, training and research opportunities. We have learned that appropriate scientific and academic mentoring is mandatory during the initial years of a junior faculty appointment, helping the individual to overcome hurdles that impede a rewarding, successful and productive academic career. Scholars will be recruited to pursue two general areas, biomedical (laboratory-based) research and clinical research, in reproductive science. In addition, two general pathways (I and II) have been established to guide relatively inexperienced (Track I) and more senior Scholars (Track II), respectively. Translational research, a burgeoning focus within our department that has benefited from long-standing multidisciplinary partnerships, will be gained through participation in studies bridging the biomedically and clinically oriented projects. We are committed to nurturing a cadre of UCSF WRHR Scholars who will improve the health status of women by conducting important discovery, expanding knowledge, and testing innovations for the prevention, diagnosis and treatment of reproductive disorders. Through our proposed mentoring program, we anticipate that our Scholars will be independent investigators and future leaders of women's reproductive health research nationally and internationally.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Physician Scientist Award (Program) (PSA) (K12)
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Study Section
Special Emphasis Panel (ZHD1-DSR-L (14))
Program Officer
Parrott, Estella C
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University of California San Francisco
Obstetrics & Gynecology
Schools of Medicine
San Francisco
United States
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Snowden, Jonathan M; Cheng, Yvonne W; Emeis, Cathy L et al. (2015) The impact of hospital obstetric volume on maternal outcomes in term, non-low-birthweight pregnancies. Am J Obstet Gynecol 212:380.e1-9
Nijagal, Malini Anand; Kuppermann, Miriam; Nakagawa, Sanae et al. (2015) Two practice models in one labor and delivery unit: association with cesarean delivery rates. Am J Obstet Gynecol 212:491.e1-8
Rosenstein, Melissa G; Vargas, Juan E; Drey, Eleanor A (2014) Ultrasound-guided instrumental removal of the retained placenta after vaginal delivery. Am J Obstet Gynecol 211:180.e1-3
Rosenstein, Melissa G; Snowden, Jonathan M; Cheng, Yvonne W et al. (2014) The mortality risk of expectant management compared with delivery stratified by gestational age and race and ethnicity. Am J Obstet Gynecol 211:660.e1-8
Cheng, Yvonne W; Snowden, Jonathan M; Handler, Stephanie J et al. (2014) Litigation in obstetrics: does defensive medicine contribute to increases in cesarean delivery? J Matern Fetal Neonatal Med 27:1668-75
Rosenstein, Melissa G; Turk, Jema K; Caughey, Aaron B et al. (2014) Dilation and evacuation training in maternal-fetal medicine fellowships. Am J Obstet Gynecol 210:569.e1-5
Cheng, Yvonne W; Snowden, Jonathan M; Handler, Stephanie et al. (2014) Clinicians' practice environment is associated with a higher likelihood of recommending cesarean deliveries. J Matern Fetal Neonatal Med 27:1220-7
Marshall, Nicole E; Guild, Camelia; Cheng, Yvonne W et al. (2014) The effect of maternal body mass index on perinatal outcomes in women with diabetes. Am J Perinatol 31:249-56
Yee, Lynn M; Cheng, Yvonne W; Inturrisi, Maribeth et al. (2013) Gestational weight loss and perinatal outcomes in overweight and obese women subsequent to diagnosis of gestational diabetes mellitus. Obesity (Silver Spring) 21:E770-4
Sparks, Teresa N; Cheng, Yvonne W; Phan, Ngoc et al. (2013) Does risk of preeclampsia differ by twin chorionicity? J Matern Fetal Neonatal Med 26:1273-7

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