This application seeks to renew the Oregon BIRCWH program entitled """"""""Scholars in Women's Health Research across the Lifespan"""""""". The goal of the program is to create a stimulating and nurturing environment for junior faculty to develop into leading Physician Scientists in Women's Health. Our program recognizes that research can modify the course of disease at one point in a woman's lifespan which will affect the rest of lifelong development and aging. The program pairs basic and clinical junior faculty scientists with established mentors from different backgrounds who have expertise in Women's Health Issues in order to enhance the scholar's research capabilities. The mix of career paths and backgrounds is integral to increasing collaboration and invigorating research in Women's Health across the lifespan. The extensive intellectual and research resources at the Oregon Health &Science University (OHSU) are available and committed to developing BIRCWH scholars. Integration is interdepartmental and is Center driven to enhance collaborations between scientists and trainees in the Center for Women's Health, the Heart Research Center, the Primate Research Center, the Cancer Institute, and the Center for Gender Biology and Medicine. Sophisticated research core laboratories specializing in Molecular Biology, Cell Culture, DNAanalysis, Imaging, Statistics,Assisted Reproductive Techniques, Endocrine Assays, Laboratory Animal, Transgenic and Molecular Genetics Cores, among others, are established and available to the BIRCWH Scholars. Advanced training in designing clinical studies and statistical evaluation for clinician scientists will be coordinated through the highly successful Human Investigations Program. Writing skills are enhanced through structured workshops. The mentors of this BIRCWH Program are accomplished and funded scientists who will provide diverse and in-depth mentorship for scholars in areas of women's health that extend across the lifespan. Our program, with its institutional commitment, multicenter interdisciplinary resources, accomplished mentors and focus on the importance of a lifespan approach has proved successful for our initial six BIRCWH Scholars. All have submitted a major independent NIH grant and five have now received funding. The BIRCWH Scholars have been successful as Principal Investigators (PI) or Co-Pis on 8 National Awards, Co-investigators on 4 National Awards and PI or Co-Pi on 16 industry or regional grants.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12HD043488-10
Application #
8132955
Study Section
Special Emphasis Panel (ZRG1-HOP-B (50))
Program Officer
Davis Nagel, Joan
Project Start
2002-09-26
Project End
2012-07-31
Budget Start
2011-08-01
Budget End
2012-07-31
Support Year
10
Fiscal Year
2011
Total Cost
$496,800
Indirect Cost
Name
Oregon Health and Science University
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239
Tilden, Ellen L; Cheyney, Melissa; Guise, Jeanne-Marie et al. (2017) Vaginal birth after cesarean: neonatal outcomes and United States birth setting. Am J Obstet Gynecol 216:403.e1-403.e8
Guise, Jeanne-Marie; Winter, Susan; Fiore, Stephen M et al. (2017) Organizational and training factors that promote team science: A qualitative analysis and application of theory to the National Institutes of Health's BIRCWH career development program. J Clin Transl Sci 1:101-107
Jurgens, Corrine Y; Lee, Christopher S; Riegel, Barbara (2017) Psychometric Analysis of the Heart Failure Somatic Perception Scale as a Measure of Patient Symptom Perception. J Cardiovasc Nurs 32:140-147
Schenning, Katie J; Noguchi, Kevin K; Martin, Lauren Drew et al. (2017) Isoflurane exposure leads to apoptosis of neurons and oligodendrocytes in 20- and 40-day old rhesus macaques. Neurotoxicol Teratol 60:63-68
Phillippi, Julia C; Neal, Jeremy L; Carlson, Nicole S et al. (2017) Utilizing Datasets to Advance Perinatal Research. J Midwifery Womens Health :
Boone-Heinonen, J; Tillotson, C J; O'Malley, J P et al. (2017) Characterizing a ""Big Data"" Cohort of Over 200,000 Low-Income U.S. Infants and Children for Obesity Research: The ADVANCE Early Life Cohort. Matern Child Health J 21:421-431
Guise, Jeanne-Marie; Geller, Stacie; Regensteiner, Judith G et al. (2017) Team Mentoring for Interdisciplinary Team Science: Lessons From K12 Scholars and Directors. Acad Med 92:214-221
Sacks, Rebecca M; Takemoto, Erin; Andrea, Sarah et al. (2017) Childhood Maltreatment and BMI Trajectory: The Mediating Role of Depression. Am J Prev Med 53:625-633
Nakamura, Yukiko K; Janowitz, Cathleen; Metea, Christina et al. (2017) Short chain fatty acids ameliorate immune-mediated uveitis partially by altering migration of lymphocytes from the intestine. Sci Rep 7:11745
Nakamura, Yukiko K; Metea, Christina; Karstens, Lisa et al. (2016) Gut Microbial Alterations Associated With Protection From Autoimmune Uveitis. Invest Ophthalmol Vis Sci 57:3747-58

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