The long-term goal of the WRHRCDC at Northwestern University is to continue to foster and develop an outstanding mentored research training program for obstetrician-gynecologists, and to prepare our WRHR trainees (Scholars) to become independent investigators in women's health research. Since it has been first funded in 2005, our WRHRCDC has made major progress in reaching this goal. We have successfully trained 4 Scholars, who published 27 papers and received 18 grant awards including 6 from NIH, and met all our WRHRCDC benchmarks. The Dept of Ob/Gyn will continue to coordinate and administer the WRHRCDC Program and make full use of the scientific wealth and reproductive research infrastructure at Northwestern in its entirety. The key leadership at Northwestern made strong institutional commitments to the WRHRCDC Program. Sherman Elias, MD, Chair of Ob/Gyn and Serdar Bulun, MD, the Division Director of Reproductive Biology Research will continue to serve as the PI and WRHR Research Director, respectively. The Department of Ob/Gyn at Northwestern has traditionally recruited high quality residents, subspecialty fellows and junior faculty;currently 16% of this group are underrepresented minorities (URM). One of our current WRHR Scholars is an URM. Thus, we have a large and active pool of candidates for WRHR Scholar selection. These Scholars will have an opportunity to choose between highly competitive clinical research teams or laboratories conducting research in the areas of Reproductive Endocrinology and Infertility, Maternal-Fetal Medicine, Gynecologic Oncology and Reproductive Genetics and covering the reproductive portion of hypothalamic-pituitary axis, ovary, uterus, placenta and the fetus. The WRHR Scholars will interact with existing two P01, two U54, and one SCOR Center grants and one T32 training grant specifically in the area of obstetrics and gynecology. As the Northwestern WRHRCDC Program, we are fully equipped to continue to recruit top-quality obstetrician-gynecologists and train them to conduct research and compete for federal grants and retain them as they become independent investigators. Our excellent track record during the past funding period strongly supports our application.

Public Health Relevance

There is a severe shortage of physicians who conduct research in obstetrics and gynecology. During the first funding period since 2005, we have successfully developed an outstanding mentored career development program conducive to transition obstetrician/gynecologists to become independent investigators. Our trainees became extremely successful. Here, we propose to continue to improve this Program.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12HD050121-08
Application #
8247182
Study Section
Special Emphasis Panel (ZHD1-DSR-L (26))
Program Officer
Parrott, Estella C
Project Start
2005-04-27
Project End
2015-03-31
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
8
Fiscal Year
2012
Total Cost
$427,410
Indirect Cost
$42,407
Name
Northwestern University at Chicago
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Gawron, Lori M; Goldberger, Adina; Gawron, Andrew J et al. (2014) The impact of hormonal contraception on disease-related cyclical symptoms in women with inflammatory bowel diseases. Inflamm Bowel Dis 20:1729-33
Lawson, Angela K; Klock, Susan C; Pavone, Mary Ellen et al. (2014) Prospective study of depression and anxiety in female fertility preservation and infertility patients. Fertil Steril 102:1377-84
Gawron, Lori M; Hammond, Cassing; Keefer, Laurie (2014) Documentation of reproductive health counseling and contraception in women with inflammatory bowel diseases. Patient Educ Couns 94:134-7
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Facco, Francesca L; Ouyang, David W; Zee, Phyllis C et al. (2014) Implications of sleep-disordered breathing in pregnancy. Am J Obstet Gynecol 210:559.e1-6
Pavone, Mary Ellen; Hirshfeld-Cytron, Jennifer; Tingen, Candace et al. (2014) Human ovarian tissue cortex surrounding benign and malignant lesions. Reprod Sci 21:582-9
Ono, Masanori; Yin, Ping; Navarro, Antonia et al. (2014) Inhibition of canonical WNT signaling attenuates human leiomyoma cell growth. Fertil Steril 101:1441-9
Yee, Lynn M; Simon, Melissa A (2014) The role of health literacy and numeracy in contraceptive decision-making for urban Chicago women. J Community Health 39:394-9
Gawron, Lori M; Gawron, Andrew J; Kasper, Amanda et al. (2014) Contraceptive method selection by women with inflammatory bowel diseases: a cross-sectional survey. Contraception 89:419-25
Facco, Francesca L; Ouyang, David W; Zee, Phyllis C et al. (2014) Sleep disordered breathing in a high-risk cohort prevalence and severity across pregnancy. Am J Perinatol 31:899-904

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