This application seeks support for our application for the Men's Reproductive Health Research Training Grant to the Center for Reproductive Medicine and the Scott Department of Urology at Baylor College of Medicine. The research emphasis of this program is in the areas of pediatric urology/genitourinary development, steroid hormone action, stem cells and male reproductive biology/male infertility. The training faculty includes 7 Ph.D/M.D., Ph.D. faculty and11 M.D.s. Dr. Lamb will serve as both the Program Director and the Research Director of the MRHR training program. Drs. Lipshultz, Gonzales, Cisek, Khera, Roth, and Janzen will ensure the trainees are optimally trained in the urologic subspecialty areas of male infertility and pediatric urology. The major research areas in the program include: genetics and genomics of genitourinary developmental defects, cell biology, steroid hormone receptors, male reproductive biology/infertility, genetics, cell cycle control, ste cells, gene therapy and gene disruption. The trainees will be M.D. junior faculty members at Baylor College of Medicine. Our program attracts highly qualified trainees who seek intensive and substantial research training in men's reproductive health research with an emphasis on clinical translation. We have a defined recruitment plan that emphasizes the recruitment of women and minorities. The strengths of the training environment include highly respected, well-funded, experienced faculty, the high national ranking for NIH funding of Urology/Cell Biology and Pathology departments, a structured mentoring program and required coursework, a cell biology graduate program with relevant course work and depth in both cell biology and genetics. Our long-term goal is to train these young investigators to successfully compete for peer-reviewed funding and eventually to increase basic and translational research efforts in men's reproductive health research.

Public Health Relevance

This MRHR application will train new investigators to become clinical and basic researchers in men's health issues. This program will offer training in both basic and clinical research to investigators to improve men's health.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Physician Scientist Award (Program) (PSA) (K12)
Project #
5K12HD073917-02
Application #
8546440
Study Section
Special Emphasis Panel (ZHD1-DSR-L (54))
Program Officer
Moss, Stuart B
Project Start
2012-09-18
Project End
2017-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
2
Fiscal Year
2013
Total Cost
$344,819
Indirect Cost
$25,542
Name
Baylor College of Medicine
Department
Urology
Type
Schools of Medicine
DUNS #
051113330
City
Houston
State
TX
Country
United States
Zip Code
77030
Pathak, Piyush; Chandrashekar, Aravind; Hakky, Tariq S et al. (2016) Varicocele management in the era of in vitro fertilization/intracytoplasmic sperm injection. Asian J Androl 18:343-8
Yuruk, E; Pastuszak, A W; Suggs 3rd, J M et al. (2016) The association between seminal vesicle size and duration of abstinence from ejaculation. Andrologia :
Rodriguez, Katherine M; Pastuszak, Alexander W; Lipshultz, Larry I (2016) Enclomiphene citrate for the treatment of secondary male hypogonadism. Expert Opin Pharmacother 17:1561-7
Kohn, Taylor P; Louis, Matthew R; Pickett, Stephen M et al. (2016) Age and duration of testosterone therapy predict time to return of sperm count after human chorionic gonadotropin therapy. Fertil Steril :
Nguyen, Taylor M; Pastuszak, Alexander W (2016) Testosterone Therapy Among Prostate Cancer Survivors. Sex Med Rev 4:376-88
Herati, Amin S; Pastuszak, Alexander W (2016) The Genetic Basis of Peyronie's Disease: A Review. Sex Med Rev 4:85-94
Chiba, Koji; Ramasamy, Ranjith; Lamb, Dolores J et al. (2016) The varicocele: diagnostic dilemmas, therapeutic challenges and future perspectives. Asian J Androl 18:276-81
Hollander, Adam B; Pastuszak, Alexander W; Hsieh, Tung-Chin et al. (2016) Cabergoline in the Treatment of Male Orgasmic Disorder-A Retrospective Pilot Analysis. Sex Med 4:e28-33
Desroches, Bethany; Kohn, Taylor P; Welliver, Charles et al. (2016) Testosterone therapy in the new era of Food and Drug Administration oversight. Transl Androl Urol 5:207-12
Ramasamy, Ranjith; Lipshultz, Larry I (2015) Mixed associations observed between advanced paternal age and psychiatric morbidity in offspring. Evid Based Ment Health 18:10

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