The specific aim of the Midcareer investigator Award in Patient-Oriented Research is to provide the Principal Investigator with sufficient protected time in order: 1) to expand a research program devoted to enhancing the frequency and quality of shared decision-making for older persons in order to provide patients with care that best meets their treatment preferences and 2) to formalize a mentorship program focused on providing interdiscplinary mentorship to trainees from a diverse range of disciplines and schools pursuing aging research. The research program will build upon Dr. Fried's past work to: a) utilize health behavior models to explicate advance care planning as a health behavior and b) develop methods to elicit the preferences of older persons with multiple comorbidities. This program will utilize mixed qualitative- quantitative methods to provide greater insight into older persons'experiences with and perceptions of difficult treatment decision-making and to develop patient-centered measures. The mentorship program will utilize the resources described below to provide core educational and career development experiences. Building upon these, the trainee's individual research program will serve as the core of the mentorship program, and it will be supplemented by mentorship regarding skills critical to a successful research career and specific career guidance. The mentorship program will be based on an explicit consideration and documentation of the trainee's goals, a mentorship plan tailored to meet these goals, and regular review of how well the plan is assisting the trainee to meet his/her goals. The environment of the Yale School of Medicine offers extensive resources to support both the research and mentorship programs. These include a number of training programs that attract a large number of talented post-doctoral fellows and that provide well-developed curricula, opportunities for advanced didactic training in biostatistics, epidemiology, and health policy, and, through the Yale Program on Aging/Pepper Center, a research infrastructure providing skilled field, data management, and biostatistical support as well as access to a broad range of populations. In addition, the research and mentorship programs will utilize and continue to build the interdisciplinary relationships Dr. Fried has established with medical subspecialties, psychiatry, and the Schools of Nursing and Public Health.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Midcareer Investigator Award in Patient-Oriented Research (K24)
Project #
Application #
Study Section
National Institute on Aging Initial Review Group (NIA)
Program Officer
Nielsen, Lisbeth
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Budget End
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Fiscal Year
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Yale University
Internal Medicine/Medicine
Schools of Medicine
New Haven
United States
Zip Code
Hopper, Katriina; Fried, Terri R; Pisani, Margaret A (2015) Health care worker attitudes and identified barriers to patient sleep in the medical intensive care unit. Heart Lung 44:95-9
Case, Siobhan M; O'Leary, John; Kim, Nancy et al. (2014) Relationship between universal health outcome priorities and willingness to take medication for primary prevention of myocardial infarction. J Am Geriatr Soc 62:1753-8
Amjad, Halima; Towle, Virginia; Fried, Terri (2014) Association of experience with illness and end-of-life care with advance care planning in older adults. J Am Geriatr Soc 62:1304-9
Dodson, John A; Fried, Terri R; Van Ness, Peter H et al. (2013) Patient preferences for deactivation of implantable cardioverter-defibrillators. JAMA Intern Med 173:377-9
Case, Siobhan M; Fried, Terri R; O'Leary, John (2013) How to ask: older adults' preferred tools in health outcome prioritization. Patient Educ Couns 91:29-36
Thomas, John M; Cooney Jr, Leo M; Fried, Terri R (2013) Systematic review: Health-related characteristics of elderly hospitalized adults and nursing home residents associated with short-term mortality. J Am Geriatr Soc 61:902-11
Case, Siobhan M; Towle, Virginia R; Fried, Terri R (2013) Considering the balance: development of a scale to assess patient views on trade-offs in competing health outcomes. J Am Geriatr Soc 61:1331-6
Tinetti, Mary E; Fried, Terri R; Boyd, Cynthia M (2012) Designing health care for the most common chronic condition--multimorbidity. JAMA 307:2493-4
Erekson, Elisabeth A; Ratner, Elena S; Walke, Lisa M et al. (2012) Gynecologic surgery in the geriatric patient. Obstet Gynecol 119:1262-9
Fried, Terri R; Vaz Fragoso, Carlos A; Rabow, Michael W (2012) Caring for the older person with chronic obstructive pulmonary disease. JAMA 308:1254-63

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