Project Description This is a competing renewal application for a K24 Mid-Career Award in Patient-Oriented Research for Joseph M. Vinetz, M.D. of the University of California San Diego. The applicant's original award proposed to provide support for patient oriented research on tropical diseases including malaria and leptospirosis with a particularly emphasis on the mentoring of junior physician-scholar trainees at all levels. These goals were met as demonstrated by publications, new research and training grants to support patient-oriented research and career advancement of mentees including patient-oriented career research awards from the NIH. In the new project period, patient-oriented research projects in malaria, leptospirosis, and brucellosis are proposed as vehicles to mentor junior physician scientists at all levels leveraging funded NIH grants. Substantial emphasis is placed on recruiting a diverse workforce and on formal training in the responsible conduct of research. Research projects will take place in the U.S., Peru and Brazil.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Midcareer Investigator Award in Patient-Oriented Research (K24)
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Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Program Officer
Rao, Malla R
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University of California San Diego
Internal Medicine/Medicine
Schools of Medicine
La Jolla
United States
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Fouts, Derrick E; Matthias, Michael A; Adhikarla, Haritha et al. (2016) What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira. PLoS Negl Trop Dis 10:e0004403
Agampodi, Suneth B; Dahanayaka, Niroshan J; Nöckler, Karsten et al. (2016) Redefining Gold Standard Testing for Diagnosing Leptospirosis: Further Evidence from a Well-Characterized, Flood-Related Outbreak in Sri Lanka. Am J Trop Med Hyg 95:531-6
Llanos-Chea, Fiorella; Martínez, Dalila; Rosas, Angel et al. (2015) Characteristics of Travel-Related Severe Plasmodium vivax and Plasmodium falciparum Malaria in Individuals Hospitalized at a Tertiary Referral Center in Lima, Peru. Am J Trop Med Hyg 93:1249-53
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Chuquiyauri, Raul; Molina, Douglas M; Moss, Eli L et al. (2015) Genome-Scale Protein Microarray Comparison of Human Antibody Responses in Plasmodium vivax Relapse and Reinfection. Am J Trop Med Hyg 93:801-9
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Cannella, Anthony P; Arlehamn, Cecilia S Lindestam; Sidney, John et al. (2014) Brucella melitensis T cell epitope recognition in humans with brucellosis in Peru. Infect Immun 82:124-31

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