To address the CTSA vision to have a sustained and transformative influence on the quality and value of clinical &translational research, leadership from three academic institutions - Emory University, Morehouse School of Medicine, and Georgia Institute of Technology, along with other collaborative organizations formed in 2007, the Atlanta Clinical and Translational Science Institute (ACTSI). The ACTSI has integrated discovery, education, training and community engagement programs and engendered an unprecedented level of transformation in clinical and translational research in our community. The ACTSI has developed an Atlanta """"""""home"""""""" for clinical and translational research through support of: 673 investigators, 520 projects, 93 pilot projects in 96 research areas, over 193 federal (PHS) grants, 134 current or graduated MSCR, KL, or TL scholars, and over 75 additional active trainees. ACTSI support has also contributed to 661 scientific publications, tripled inter-institutional collaborations, and led to important scientific breakthroughs in clinical and translational science. Guided by the mission, """"""""[through ethical community engagement, focused education and training, and innovative support of discovery, the collaborative partners of the ACTSI rapidly and efficiently translate scientific discoveries to impact all populations of the Atlanta community,"""""""" in the next five years, eleven key function programs will be charged with implementing three expanded specific aims.
Aim 1 : Promote discovery through inter-disciplinary collaboration, the development of novel and emerging technologies, drugs, devices, diagnostics and biologies, and the efficient translation of these discoveries to benefit human health.
Aim 2 : Expand and improve outstanding programs to educate and train a growing cadre of ethnically diverse, clinician scientists, and increase the capacity and infrastructure to foster multidisciplinary translational research teams.
Aim 3 : Actively engage the community in research that will engender the public trust in scientific discovery and the translation of new knowledge that ultimately enhances the health of the communities we serve.
Created in response to the NIH CTSA program, the Atlanta CTSI serves as a catalyst and incubator for clinical and translational research across Georgia and with regional and national impact. The goals are to create and accelerate clinical and translational science discovery, build interdisciplinary research capacity, engage communities in health sciences activities, develop new research tools and information technologies, and build the careers of clinical/translational scientists of the future.
|Kempker, Jordan A; Martin, Greg S (2017) Using Sepsis-3 to identify infected patients with high mortality risk. Lancet Infect Dis 17:573-575|
|O'Neal, Wesley T; Hammadah, Muhammad; Sandesara, Pratik B et al. (2017) The association between acute mental stress and abnormal left atrial electrophysiology. J Cardiovasc Electrophysiol 28:1151-1157|
|Pakvasa, Mitali A; Winkler, Anne M; Hamrick, Shannon E et al. (2017) Observational study of haemostatic dysfunction and bleeding in neonates with hypoxic-ischaemic encephalopathy. BMJ Open 7:e013787|
|Westney, Gloria; Foreman, Marilyn G; Xu, Junjun et al. (2017) Impact of Comorbidities Among Medicaid Enrollees With Chronic Obstructive Pulmonary Disease, United States, 2009. Prev Chronic Dis 14:E31|
|Reinertsen, Erik; Nemati, Shamim; Vest, Adriana N et al. (2017) Heart rate-based window segmentation improves accuracy of classifying posttraumatic stress disorder using heart rate variability measures. Physiol Meas 38:1061-1076|
|McGuirk, Joseph; Waller, Edmund K; Qayed, Muna et al. (2017) Building blocks for institutional preparation of CTL019 delivery. Cytotherapy 19:1015-1024|
|Holder, Andre L; Overton, Elizabeth; Lyu, Peter et al. (2017) Serial Daily Organ Failure Assessment Beyond ICU Day 5 Does Not Independently Add Precision to ICU Risk-of-Death Prediction. Crit Care Med 45:2014-2022|
|Marts, Lucian T; Kempker, Jordan A; Martin, Greg S (2017) Fluid Management in Acute Respiratory Distress Syndrome: Do We Have All the FACTTs to Determine the Effect of Race? Ann Am Thorac Soc 14:1391-1392|
|Patel, Ravi M; Zimmerman, Kanecia; Carlton, David P et al. (2017) Early Caffeine Prophylaxis and Risk of Failure of Initial Continuous Positive Airway Pressure in Very Low Birth Weight Infants. J Pediatr 190:108-111.e1|
|Comeau, Dawn L; Escoffery, Cam; Freedman, Ariela et al. (2017) Improving clinical and translational research training: a qualitative evaluation of the Atlanta Clinical and Translational Science Institute KL2-mentored research scholars program. J Investig Med 65:23-31|
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