Neutrophil elastase inhibition may be beneficial in cystic fibrosis (CF). This multi-center study examines a putative neutrophil elastase inhibitor, DMP-777, with respect to safety, tolerability, pharmacokinetics, and pharmacodynamics in adult patients with CF. Five subjects will be admitted to the inpatient unit for two days on two separate occasions for extensive evaluation including timed blood draws.

Project Start
1997-12-01
Project End
1998-11-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
36
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Type
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
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