The goal of this study is to assess and compare the hypothalmic-pituitary-adrenal axis (HPA) function in patients with idiopathic insomnia and hypersomnia related to another mental disorder whose chief complaint is daytime somnolence and whose degree of excessive daytime sleepiness has been objectively measured in the sleep laboratory. Our hypothesis is that idiopathic hypersomnia is associated with hypofunctioning of the HPA axis compared to another mental disorder and to normal controls.

Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Sterling, Nicholas W; Du, Guangwei; Lewis, Mechelle M et al. (2017) Cortical gray and subcortical white matter associations in Parkinson's disease. Neurobiol Aging 49:100-108
Berryman, Claire E; Fleming, Jennifer A; Kris-Etherton, Penny M (2017) Inclusion of Almonds in a Cholesterol-Lowering Diet Improves Plasma HDL Subspecies and Cholesterol Efflux to Serum in Normal-Weight Individuals with Elevated LDL Cholesterol. J Nutr 147:1517-1523
Liu, Guodong; Sterling, Nicholas W; Kong, Lan et al. (2017) Statins may facilitate Parkinson's disease: Insight gained from a large, national claims database. Mov Disord 32:913-917
Quick, Virginia; Byrd-Bredbenner, Carol; Shoff, Suzanne et al. (2016) Relationships of Sleep Duration With Weight-Related Behaviors of U.S. College Students. Behav Sleep Med 14:565-80
Mayes, Susan D; Waxmonsky, James D; Calhoun, Susan L et al. (2016) Disruptive Mood Dysregulation Disorder Symptoms and Association with Oppositional Defiant and Other Disorders in a General Population Child Sample. J Child Adolesc Psychopharmacol 26:101-6
Lewis, Mechelle M; Flynn, Michael R; Lee, Eun-Young et al. (2016) Longitudinal T1 relaxation rate (R1) captures changes in short-term Mn exposure in welders. Neurotoxicology 57:39-44
Sterling, Nicholas W; Wang, Ming; Zhang, Lijun et al. (2016) Stage-dependent loss of cortical gyrification as Parkinson disease ""unfolds"". Neurology 86:1143-51
Wagner, Daymond; Eslinger, Paul J; Barrett, A M (2016) Decreased leftward 'aiming' motor-intentional spatial cuing in traumatic brain injury. Neuropsychology 30:731-41
Karunanayaka, Prasanna R; Lee, Eun-Young; Lewis, Mechelle M et al. (2016) Default mode network differences between rigidity- and tremor-predominant Parkinson's disease. Cortex 81:239-50
Sterling, N W; Lewis, M M; Du, G et al. (2016) Structural Imaging and Parkinson's Disease: Moving Toward Quantitative Markers of Disease Progression. J Parkinsons Dis 6:557-67

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