Is it true that males are healthier than females but die younger? If so, why? We plan demographic analyses to address these two overarching questions concerning the health-survival paradox. First, to what extent is the paradox true? How general is it? * According to which definitions and measures and along which dimensions are men healthier than women? * How do male-female morbidity and mortality differences vary with age? * How do they vary over place? * How have they varied over time? * How do they vary across species of mammals, birds, reptiles, amphibians and fish? Second, to the extent that the paradox is true, why is this the case? Various social and biological hypotheses will be tested by analyzing: Human and nonhuman lifetables (Project 1); Survey and register data on humans in Denmark (Project 2); Survey data on humans in the United States (Project 3) and in Japan, the Philippines and Singapore (Project 4); Longitudinal observations on baboons in the wild in Kenya (Project 5); Longitudinal data on lemurs in the wild on Madagascar and in captivity at Duke and in France (Project 6);and Laboratory data on fruit flies (Project 7). The combination of informative animal models and high-quality human data and sophisticated demographic analyses will provide a deeper understanding of the basis for sex differences in health and survival and of opportunities to reduce these differences.
Is it true that males are healthier than females but die younger? If so, why? This program project supports research projects that address these questions concerning the human health-survival paradox. Findings will provide a deeper understanding of the basis for sex differences in health and survival-and of the opportunities that society and particularly health professionals have to improve health and survival for males and females.
|Jones, Owen R; Scheuerlein, Alexander; Salguero-Gomez, Roberto et al. (2014) Diversity of ageing across the tree of life. Nature 505:169-73|
|Oksuzyan, A; Shkolnikova, M; Vaupel, J W et al. (2014) Sex differences in health and mortality in Moscow and Denmark. Eur J Epidemiol 29:243-52|
|Gesquiere, Laurence R; Ziegler, Toni E; Chen, Patricia A et al. (2014) Measuring fecal testosterone in females and fecal estrogens in males: comparison of RIA and LC/MS/MS methods for wild baboons (Papio cynocephalus). Gen Comp Endocrinol 204:141-9|
|Archie, Elizabeth A; Tung, Jenny; Clark, Michael et al. (2014) Social affiliation matters: both same-sex and opposite-sex relationships predict survival in wild female baboons. Proc Biol Sci 281:|
|Onyango, Patrick O; Gesquiere, Laurence R; Altmann, Jeanne et al. (2013) Puberty and dispersal in a wild primate population. Horm Behav 64:240-9|
|Alberts, Susan C; Altmann, Jeanne; Brockman, Diane K et al. (2013) Reproductive aging patterns in primates reveal that humans are distinct. Proc Natl Acad Sci U S A 110:13440-5|
|Runcie, Daniel E; Wiedmann, Ralph T; Archie, Elizabeth A et al. (2013) Social environment influences the relationship between genotype and gene expression in wild baboons. Philos Trans R Soc Lond B Biol Sci 368:20120345|
|Lindahl-Jacobsen, Rune; Hanson, Heidi A; Oksuzyan, Anna et al. (2013) The male-female health-survival paradox and sex differences in cohort life expectancy in Utah, Denmark, and Sweden 1850-1910. Ann Epidemiol 23:161-6|
|Babbitt, Courtney C; Tung, Jenny; Wray, Gregory A et al. (2012) Changes in gene expression associated with reproductive maturation in wild female baboons. Genome Biol Evol 4:102-9|
|Gesquiere, Laurence R; Onyango, Patrick O; Alberts, Susan C et al. (2011) Endocrinology of year-round reproduction in a highly seasonal habitat: environmental variability in testosterone and glucocorticoids in baboon males. Am J Phys Anthropol 144:169-76|
Showing the most recent 10 out of 14 publications