The Administrative Core will continue coordinating the different activities of the four Projects and three Cores of this Program Project. The long-term goal of this Core is to serve as the center of integration for the different parts of this collaborative effort and as a liaison of this program with components in and outside our school.
The specific aims of the core are: 1) to provide the members of the Program Project with the administrative and secretarial support required for the functioning of their programs, 2) to integrate the results obtained by each project, 3) to coordinate approval for transferring of materials and reagents to other members of the scientific community, 4) to facilitate communication among the different members of the PP, 5) to monitor and evaluate the scientific progress of the PP, 6) to promote interactions of the PP with other Program Projects and Centers with related interests in our school and outside, 7) to increase awareness for aging research. The components of the core are the administrative service, the Executive Committee and the Scientific Advisory Committee. These components are overseen and coordinated by the Director of the Core. The services offered by the core include: administrative and secretarial support (ordering of reagents and supplies, financial and progress reports, assistance with budget management, handling of material transfer agreements), organization of weekly meetings, monthly works in progress and of the biannual meetings with the Scientific Advisory Committee, maintenance of the intranet system of data exchange. The key personnel of the core are the director, the administrator and the secretary. The director oversees and coordinates all the activities of the core and meets periodically with the administrator (to review the financial reports), with the Executive Committee (to review and evaluate the performance of the different integral parts of the program) and with the Scientific Advisory Committee (to review and evaluate the scientific progress of the Program Project). The administrator and the secretary assist the investigators with financial matters, the organization of meetings and conferences and the day-to-day needs for the proper functioning of the Program. Relevance: This core is essential for the integration of the projects and cores into a cohesive program that allows for faster and more efficient progress toward the elucidation of the molecular basis for the functional decline of cells, organs and systems with age. The basis for this cohesive program is the free and efficient communication of scientific results among the members of the program, the active review of progress and utilization of resources and the delineation of a common future goal and direction.
This core is essential for the integration of the projects and cores into a cohesive program that allows for faster and more efficient progress toward the elucidation of the molecular basis for the functional decline of cells, organs and systems with age. The basis for this cohesive program is the free and efficient communication of scientific results among the members of the program, the active review of progress and utilization of resources and the delineation of a common future goal and direction.
|Batista-Gonzalez, Ana; Singh, Rajat (2017) Lysosomal function in ?-cell survival during glucolipotoxicity. Ann Transl Med 5:471|
|Satori, Chad P; Ramezani, Marzieh; Koopmeiners, Joseph S et al. (2017) Checkpoints for Preliminary Identification of Small Molecules found Enriched in Autophagosomes and Activated Mast Cell Secretions Analyzed by Comparative UPLC/MSe. Anal Methods 9:46-54|
|Raz, Yotam; Guerrero-Ros, Ignacio; Maier, Andrea et al. (2017) Activation-Induced Autophagy Is Preserved in CD4+ T-Cells in Familial Longevity. J Gerontol A Biol Sci Med Sci 72:1201-1206|
|Martinez-Lopez, Nuria; Tarabra, Elena; Toledo, Miriam et al. (2017) System-wide Benefits of Intermeal Fasting by Autophagy. Cell Metab 26:856-871.e5|
|Maus, Mate; Cuk, Mario; Patel, Bindi et al. (2017) Store-Operated Ca2+ Entry Controls Induction of Lipolysis and the Transcriptional Reprogramming to Lipid Metabolism. Cell Metab 25:698-712|
|Klionsky, Daniel J (see original citation for additional authors) (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12:1-222|
|Martinez-Lopez, Nuria; Singh, Rajat (2016) Telemetric control of peripheral lipophagy by hypothalamic autophagy. Autophagy 12:1404-5|
|Martinez-Lopez, Nuria; Garcia-Macia, Marina; Sahu, Srabani et al. (2016) Autophagy in the CNS and Periphery Coordinate Lipophagy and Lipolysis in the Brown Adipose Tissue and Liver. Cell Metab 23:113-27|
|Champa, Devora; Orlacchio, Arturo; Patel, Bindi et al. (2016) Obatoclax kills anaplastic thyroid cancer cells by inducing lysosome neutralization and necrosis. Oncotarget 7:34453-71|
|Kaushik, Susmita; Cuervo, Ana Maria (2016) AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA. Autophagy 12:432-8|
Showing the most recent 10 out of 130 publications