The overall success of the proposed WHP San Francisco PPG team depends on an efficient and highly organized Administrative Core that effectively coordinates the team's efforts. The central mission of the proposed WHP-San Francisco is to generate high-quality scientific data that broadens and extends our understanding of HIV transmission and pathogenesis in women. An effective Administrative Core will help remove or reduce the obstacles that might impair the team from achieving its experimental goals. Keys to success are the orchestration of lively and informative team meetings and the nucleation of the team in a manner that promotes synergistic rather than additive scientific collaboration. Activities of the Administrative Core are organized around three specific aims:
Specific Aim 1 : To provide a sound, effective administrative structure for WHP-San Francisco that maximizes scientific productivity, promotes free and open communication among members, allows for strategic planning on a regular basis, ensures the implementation of sound fiscal practices to maximize resources, and promotes the appropriate sharing of scientific data and resources.
Specific Aim 2 : To regularly convene team meetings and to evaluate constructively the performance of all scientific projects and cores and based on need and/or performance, to reallocate resources in a manner that best serves the overall goals of WHP-San Francisco.
Specific Aim 3 : To ensure effective integration of WHP-San Francisco within the national WHP program. Dr. Warner Greene will serve as Director and Dr. Ruth Greenblatt as Co-Director of this Core. Drs. Greene and Greenblatt have a long history of effective collaboration. This core will be based at the Gladstone Institute of Virology and Immunology (GIVI), an institution widely recognized for the excellence of its administrative services. Additional administrative staff participating in WHP-San Francisco will include Cari Weishaar/Karina Fantillo (Gladstone Grants and Contracts), and Robin Givens (Executive Assistant, Office of the Director, GIVI). As needed, the Principal Investigator can call on Sue Cammack (Administrative Assistant, Office of the Director), John Carroll (Gladstone Graphics Department), Gary Howard and Stephen Ordway (Gladstone Editorial Department) to ensure smooth and effective operation of the project. Dr. Greene and Greenblatt are committed to ensuring that WHP-San Francisco is administered in a highly effective manner benefiting all participants.

Public Health Relevance

The Administrative Core is essential for the smooth and coordinated conduct of research within this proposed P01. This core will be responsible for creating an interactive forum for the free exchange of scientific data and ideas, establishing proactive short- and long-term planning processes, ensuring investigator accountability and maintaining rigorous financial oversight.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Research Program Projects (P01)
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Special Emphasis Panel (ZAI1-TP-A)
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J. David Gladstone Institutes
San Francisco
United States
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Chen, Joseph C; Hoffman, Jacquelyn R; Arora, Ripla et al. (2016) Cryopreservation and recovery of human endometrial epithelial cells with high viability, purity, and functional fidelity. Fertil Steril 105:501-510.e1
Shanmugasundaram, Uma; Hilton, Joan F; Critchfield, J William et al. (2016) Effects of the levonorgestrel-releasing intrauterine device on the immune microenvironment of the human cervix and endometrium. Am J Reprod Immunol 76:137-48
Oh, Sam S; Galanter, Joshua; Thakur, Neeta et al. (2015) Diversity in Clinical and Biomedical Research: A Promise Yet to Be Fulfilled. PLoS Med 12:e1001918
Goldfien, Gabriel A; Barragan, Fatima; Chen, Joseph et al. (2015) Progestin-Containing Contraceptives Alter Expression of Host Defense-Related Genes of the Endometrium and Cervix. Reprod Sci 22:814-28
Smith-McCune, Karen; Chen, Joseph C; Greenblatt, Ruth M et al. (2015) Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study. PLoS One 10:e0129769
Gesner, Marianne; Maiti, Mekhala; Grant, Robert et al. (2014) Fluorescence-linked Antigen Quantification (FLAQ) Assay for Fast Quantification of HIV-1 p24(Gag). Bio Protoc 4:
Zirafi, Onofrio; Kim, Kyeong-Ae; Roan, Nadia R et al. (2014) Semen enhances HIV infectivity and impairs the antiviral efficacy of microbicides. Sci Transl Med 6:262ra157
Usmani, Shariq M; Zirafi, Onofrio; Müller, Janis A et al. (2014) Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen. Nat Commun 5:3508
Cavrois, Marielle; Neidleman, Jason; Greene, Warner C (2014) HIV-1 Fusion Assay. Bio Protoc 4:
Shanmugasundaram, Uma; Critchfield, J William; Pannell, Jane et al. (2014) Phenotype and functionality of CD4+ and CD8+ T cells in the upper reproductive tract of healthy premenopausal women. Am J Reprod Immunol 71:95-108

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