Behavioral Function - Core C Individuals surviving sepsis exhibit impaired cognitive function. We are modeling this process in mice. The Behavioral Function Core will subject mice to a battery of assessments of neurologic function including behavioral and cognitive tasks. In addition, the Core will assess long term potentiation in brain slices of mice. The use of a Core facility for these studies will ensure the involvement of trained personnel, standardized procedures, and standardized data analyses and so will facilitate comparability across all, projects. All Core personnel will have undergone the same training so all mice will be exposed to the same test, as well non test, stimuli.
| Chavan, Sangeeta S; Ma, Pingchuan; Chiu, Isaac M (2018) Neuro-immune interactions in inflammation and host defense: Implications for transplantation. Am J Transplant 18:556-563 |
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| Kim, Sook Young; Son, Myoungsun; Lee, Sang Eun et al. (2018) High-Mobility Group Box 1-Induced Complement Activation Causes Sterile Inflammation. Front Immunol 9:705 |
| Pavlov, Valentin A; Chavan, Sangeeta S; Tracey, Kevin J (2018) Molecular and Functional Neuroscience in Immunity. Annu Rev Immunol 36:783-812 |
| Li, Wei; Bao, Guoqiang; Chen, Weiqiang et al. (2018) Connexin 43 Hemichannel as a Novel Mediator of Sterile and Infectious Inflammatory Diseases. Sci Rep 8:166 |
| Gunasekaran, Manojkumar; Chatterjee, Prodyot K; Shih, Andrew et al. (2018) Immunization Elicits Antigen-Specific Antibody Sequestration in Dorsal Root Ganglia Sensory Neurons. Front Immunol 9:638 |
| Zanos, Theodoros P; Silverman, Harold A; Levy, Todd et al. (2018) Identification of cytokine-specific sensory neural signals by decoding murine vagus nerve activity. Proc Natl Acad Sci U S A 115:E4843-E4852 |
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| Hirano, Yohei; Yang, Weng-Lang; Aziz, Monowar et al. (2017) MFG-E8-derived peptide attenuates adhesion and migration of immune cells to endothelial cells. J Leukoc Biol 101:1201-1209 |
| Chavan, Sangeeta S; Pavlov, Valentin A; Tracey, Kevin J (2017) Mechanisms and Therapeutic Relevance of Neuro-immune Communication. Immunity 46:927-942 |
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