The Administrative Core will provide support for all three Projects, as well as scientific Core B.
The aims of the Administrative Core are to ensure and facilitate equitable distribution of resources through the.Program Project. In addition, this core will also ensure compliance with National Cancer Institute and National Institutes of Health rules and regulations. The Administrative Core will coordinate weekly research-ln-progress meetings, attended by Project Leaders and their laboratories. The Core will also coordinate weekly Core B meetings, which will function to prioritize sample processing and analysis. The Administrative Core will also function to coordinate communication between Program Project members and our External Advisory Board. Dr. Koumenis will be Core Director and will be supported by Ms. Dona Zlkowltz. Ms. Zikowitz will also provide administrative support for each of the Program Leaders and coordinate travel when External Advisory Board members travel to the University of Pennsylvania. Finally, Ms. Zikowitz will interface with grants management personnel within Department of Radiation Oncology and the Abramson Cancer Center, where this Program Project will be administered

Agency
National Institute of Health (NIH)
Type
Research Program Projects (P01)
Project #
5P01CA165997-02
Application #
8754470
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
Bu, Yiwen; Diehl, J Alan (2016) PERK Integrates Oncogenic Signaling and Cell Survival During Cancer Development. J Cell Physiol 231:2088-96
Xia, Chuan; Vijayan, Madhuvanthi; Pritzl, Curtis J et al. (2016) Hemagglutinin of Influenza A Virus Antagonizes Type I Interferon (IFN) Responses by Inducing Degradation of Type I IFN Receptor 1. J Virol 90:2403-17
Gui, Jun; Gober, Michael; Yang, Xiaoping et al. (2016) Therapeutic Elimination of the Type 1 Interferon Receptor for Treating Psoriatic Skin Inflammation. J Invest Dermatol 136:1990-2002
Zhang, Kangjian; Yin, Xiao-Fei; Yang, Yuan-Qin et al. (2016) A potent in vivo anti-tumor efficacy of novel recombinant type I interferon. Clin Cancer Res :
Xu, Zhenhua; Bu, Yiwen; Chitnis, Nilesh et al. (2016) miR-216b regulation of c-Jun mediates GADD153/CHOP-dependent apoptosis. Nat Commun 7:11422
Katlinskaya, Yuliya V; Katlinski, Kanstantsin V; Yu, Qiujing et al. (2016) Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression. Cell Rep 15:171-80
Bu, Yiwen; Diehl, J Alan (2016) Stressing out melanoma with an anti-GRP78 compound. Pigment Cell Melanoma Res 29:490-1
Katlinskaya, Yuliya V; Katlinski, Kanstantsin V; Lasri, Audrey et al. (2016) Type I Interferons Control Proliferation and Function of the Intestinal Epithelium. Mol Cell Biol 36:1124-35
Davar, Diwakar; Fuchs, Serge Y; Kirkwood, John M (2016) BRAF Inhibitors and IFNα: Plus, Minus, or Indeterminate? J Natl Cancer Inst 108:
Yu, Qiujing; Zhao, Bin; Gui, Jun et al. (2015) Type I interferons mediate pancreatic toxicities of PERK inhibition. Proc Natl Acad Sci U S A 112:15420-5

Showing the most recent 10 out of 19 publications