The Administrative Core is responsible for coordination of research activities, administration of resources, organization of research meetings and overseeing personnel placement, manuscript preparation and sub- mission, preparation of abstracts, reports, protocols for both animal (and ultimately human) research, and the supervision of budgets. This Core will work on a weekly basis with the Project Leaders, and facilitate science and technical support from the Cores, in order to accomplish the main objectives of the Program, maintain budgets and constructive interaction through meetings and electronic communications. The Administration will also prepare and ensure IRB and animal certifications are active, prepare annual reports, and motivate and support dissemination of Program research results.

Public Health Relevance

The Administrative Core will overview the day-to-day workings of the projects, the interaction between and co-ordination between the different projects in order to facilitate them in meeting their scientific goals.
It aims facilitate communication, organize the meetings of the entire project, and provide administrative manage- ment.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Research Program Projects (P01)
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Special Emphasis Panel (ZCA1-RPRB-W (J1))
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Brigham and Women's Hospital
United States
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Kobus, Thiele; Vykhodtseva, Natalia; Pilatou, Magdalini et al. (2016) Safety Validation of Repeated Blood-Brain Barrier Disruption Using Focused Ultrasound. Ultrasound Med Biol 42:481-92
Kobus, Thiele; Zervantonakis, Ioannis K; Zhang, Yongzhi et al. (2016) Growth inhibition in a brain metastasis model by antibody delivery using focused ultrasound-mediated blood-brain barrier disruption. J Control Release 238:281-8
Top, Can Barış; White, P Jason; McDannold, Nathan J (2016) Nonthermal ablation of deep brain targets: A simulation study on a large animal model. Med Phys 43:870-82
Sassaroli, Elisabetta; Vykhodtseva, Natalia (2016) Acoustic neuromodulation from a basic science prospective. J Ther Ultrasound 4:17
McDannold, Nathan; Livingstone, Margaret; Top, Can Barış et al. (2016) Preclinical evaluation of a low-frequency transcranial MRI-guided focused ultrasound system in a primate model. Phys Med Biol 61:7664-7687
Arvanitis, Costas D; Vykhodtseva, Natalia; Jolesz, Ferenc et al. (2016) Cavitation-enhanced nonthermal ablation in deep brain targets: feasibility in a large animal model. J Neurosurg 124:1450-9
McDannold, Nathan; Zhang, Yongzhi; Vykhodtseva, Natalia (2016) Nonthermal ablation in the rat brain using focused ultrasound and an ultrasound contrast agent: long-term effects. J Neurosurg 125:1539-1548
Aryal, Muna; Park, Juyoung; Vykhodtseva, Natalia et al. (2015) Enhancement in blood-tumor barrier permeability and delivery of liposomal doxorubicin using focused ultrasound and microbubbles: evaluation during tumor progression in a rat glioma model. Phys Med Biol 60:2511-27
Tang, Sai Chun; McDannold, Nathan J (2015) Power Loss Analysis and Comparison of Segmented and Unsegmented Energy Coupling Coils for Wireless Energy Transfer. IEEE J Emerg Sel Top Power Electron 3:215-225
Kobus, Thiele; McDannold, Nathan (2015) Update on Clinical Magnetic Resonance-Guided Focused Ultrasound Applications. Magn Reson Imaging Clin N Am 23:657-67

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