The goal of tobacco regulations is to improve public health. Tobacco regulations, however, are often implemented before they have been tested in a research setting, thereby increasing the likelihood of untoward effects caused by such regulations. The goal of this project is to use the Experimental Tobacco Marketplace to empirically assess the effects of regulatory changes on tobacco consumption among smokers.
The specific aims will address how factors such as dose, price, environmental constraints (smoke-free work environments), and flavors affect consumption and substitutability of cigarettes and vaporized nicotine products. In these within-subject studies, the research team will examine choices in the Experimental Tobacco Marketplace with some purchases actualized. This novel method will increase the external validity of modern regulatory science. Moreover, the obtained results will help direct policymakers' decisions about the availability and pricing of alternative, potentially less harmful, tobacco products.

Public Health Relevance

The number one preventable cause of mortality and morbidity in the US is cigarette smoking. Identifying policies to reduce or eliminate smoking should therefore be a primary goal of regulatory science. The overall goal of this project is to experimentally assess the factors that influence tobacco consumption and consumer behavior. Testing proposed policy changes, such as restrictions on vaporized nicotine product use, in a laboratory setting before enacting them will help to identify any untoward, unanticipated effects and bolster the successful implementation of such policies within society.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Research Program Projects (P01)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Medical University of South Carolina
United States
Zip Code
Dunbar, Zachary R; Das, Ananth; O'Connor, Richard J et al. (2018) Brief Report: Lead Levels in Selected Electronic Cigarettes from Canada and the United States. Int J Environ Res Public Health 15:
Ma, Bernice Hua; Yong, Hua-Hie; Borland, Ron et al. (2018) Factors associated with future intentions to use personal vaporisers among those with some experience of vaping. Drug Alcohol Rev 37:216-225
Bickel, Warren K; Mellis, Alexandra M; Snider, Sarah E et al. (2018) 21st century neurobehavioral theories of decision making in addiction: Review and evaluation. Pharmacol Biochem Behav 164:4-21
Stein, Jeffrey S; Heckman, Bryan W; Pope, Derek A et al. (2018) Delay discounting and e-cigarette use: An investigation in current, former, and never cigarette smokers. Drug Alcohol Depend 191:165-173
Lee, Cheolmin; Yong, Hua-Hie; Borland, Ron et al. (2018) Acceptance and patterns of personal vaporizer use in Australia and the United Kingdom: Results from the International Tobacco Control survey. Drug Alcohol Depend 185:142-148
Heckman, Bryan W; Cummings, K Michael; Stoltman, Jonathan J K et al. (2018) Longer duration of smoking abstinence is associated with waning cessation fatigue. Behav Res Ther :
Wadsworth, Elle; Hammond, David (2018) Differences in patterns of cannabis use among youth: Prevalence, perceptions of harm and driving under the influence in the USA where non-medical cannabis markets have been established, proposed and prohibited. Drug Alcohol Rev 37:903-911
Yong, Hua-Hie; Borland, Ron; Cummings, K Michael et al. (2018) Do predictors of smoking relapse change as a function of duration of abstinence? Findings from the United States, Canada, United Kingdom and Australia. Addiction 113:1295-1304
Levy, David T; Borland, Ron; Lindblom, Eric N et al. (2018) Potential deaths averted in USA by replacing cigarettes with e-cigarettes. Tob Control 27:18-25
Levy, David T; Tam, Jamie; Kuo, Charlene et al. (2018) The Impact of Implementing Tobacco Control Policies: The 2017 Tobacco Control Policy Scorecard. J Public Health Manag Pract 24:448-457

Showing the most recent 10 out of 21 publications