The Administrative Core supports productive interactions between the different projects and cores, and facilitates communication and data exchange between all associated personnel and the external advisory board (EAB). The Administrative Core will monitor the progress of each project, and the effective utilization of service core resources. Importantly, the core will provide fiscal management ensuring that all funds are utilized efficiently to support the Program Project's mission. A key core activity is to organize an annual review by the EAB, which will be done in the context of a Program Project retreat, where project leaders and trainees will report on scientific progress. This event will complement the bi-monthly project leader and IEC member meetings, and will foster integrated scientific interactions between scientists working in the project leaders' laboratories and core facilities. In addition, the core will facilitate training sessions enabling trainees at Tulane to receive hands-on training at UF in Recombinant Viral Genetics (Core C), and to provide hands-on bioinformatics training at Tulane (Core B) for UF trainees. We note that travel costs for these training-specific activities will be provided as institutional support by the University of Florida. Core A will support the timely publication of findings from the P01 components. Provision of Biostatistics services will be coordinated by Core A. Finally, the core will securely archive research data, share data between groups, and disseminate results with the scientific community after publication. To facilitate these goals, the core will create a Program Project-specific website in close coordination with Core B and Core C.

Public Health Relevance

The Administrative Core provides financial and administrative oversight and facilitates communication between the program projects and service cores. As such, it plays a key role in the success of the program, which is focused on understanding how viral and host long noncoding RNAs contribute to gamma-herpesvirus-associated disease and cancer.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA214091-03
Application #
9648128
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2019-02-01
Budget End
2020-01-31
Support Year
3
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Florida
Department
Type
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
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Sethuraman, Sunantha; Thomas, Merin; Gay, Lauren A et al. (2018) Computational analysis of ribonomics datasets identifies long non-coding RNA targets of ?-herpesviral miRNAs. Nucleic Acids Res 46:8574-8589
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Gay, Lauren A; Sethuraman, Sunantha; Thomas, Merin et al. (2018) Modified Cross-Linking, Ligation, and Sequencing of Hybrids (qCLASH) Identifies Kaposi's Sarcoma-Associated Herpesvirus MicroRNA Targets in Endothelial Cells. J Virol 92:
Mei, Suyu; Flemington, Erik K; Zhang, Kun (2018) Transferring knowledge of bacterial protein interaction networks to predict pathogen targeted human genes and immune signaling pathways: a case study on M. tuberculosis. BMC Genomics 19:505
Gay, Lauren A; Turner, Peter C; Renne, Rolf (2018) Contemporary Ribonomics Methods for Viral microRNA Target Analysis. Noncoding RNA 4:
Tonnessen-Murray, Crystal; Ungerleider, Nathan A; Rao, Sonia G et al. (2018) p53 Mediates Vast Gene Expression Changes That Contribute to Poor Chemotherapeutic Response in a Mouse Model of Breast Cancer. Transl Oncol 11:930-940
Zhang, Wensheng; Flemington, Erik K; Zhang, Kun (2018) Driver gene mutations based clustering of tumors: methods and applications. Bioinformatics 34:i404-i411

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