The Administrative Core of the Program Project Grant (PPG) serves several straightforward functions. First, it establishes the scientific priorities and directions of the research through regular meetings of the PPG's Executive Committee. As well, the Core ensures the effective integration of the PPG's three subcontracts in our program of research. We have been functionally extremely well as a highly coordinated team for many years. Second, the Core is responsible for administering the day-to-day activities of the PPG. This includes the expenditure of funds for personnel, equipment, supplies, and miscellaneous expenses according to the established budget. This also includes purchase of general supplies and maintenance of shared equipment. In addition, management of radioactivity ordering and waste disposal, hazardous waste storage and disposal, and related University requirements associated with PPG research activities are covered by the Core. Third, the Core supports visits to Dallas by members of our outstanding External Advisory Committee, and selected consultants, to meet with PPG faculty and review the progress of the research programs. Fourth, the Core supports a member of the UT Southwestern faculty to provide overall statistical support to PPG investigators. Substantial additional statistical expertise is available in Project 3 for our chromatin and gene regulation research. Fifth, the Core maintains a PPG webpage to foster communication among PPG investigators and with the scientific community and general public at large. The Core also fosters several additional outreach efforts to community organizations. Sixth, the Core, through the Executive Committee and other PPG faculty, works to ensure the successful career paths of numerous junior faculty and pre- and postdoctoral trainees, including the recruitment and retention of women and minority scientists. Seventh, the Core is responsible, in collaboration with our various training programs, to ensure the safe and ethical conduct of research.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Program Projects (P01)
Project #
3P01DA008227-21S1
Application #
8684704
Study Section
Special Emphasis Panel (ZDA1-RXL-E)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2013-12-30
Support Year
21
Fiscal Year
2013
Total Cost
$356,365
Indirect Cost
$37,357
Name
Icahn School of Medicine at Mount Sinai
Department
Type
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029
Gokce, Ozgun; Stanley, Geoffrey M; Treutlein, Barbara et al. (2016) Cellular Taxonomy of the Mouse Striatum as Revealed by Single-Cell RNA-Seq. Cell Rep 16:1126-37
Fuccillo, Marc V; Rothwell, Patrick E; Malenka, Robert C (2016) From Synapses to Behavior: What Rodent Models Can Tell Us About Neuropsychiatric Disease. Biol Psychiatry 79:4-6
Kozlenkov, Alexey; Wang, Minghui; Roussos, Panos et al. (2016) Substantial DNA methylation differences between two major neuronal subtypes in human brain. Nucleic Acids Res 44:2593-612
Cahill, Michael E; Bagot, Rosemary C; Gancarz, Amy M et al. (2016) Bidirectional Synaptic Structural Plasticity after Chronic Cocaine Administration Occurs through Rap1 Small GTPase Signaling. Neuron 89:566-82
Calipari, Erin S; Bagot, Rosemary C; Purushothaman, Immanuel et al. (2016) In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward. Proc Natl Acad Sci U S A 113:2726-31
Wang, Tianyuan; Santos, Janine H; Feng, Jian et al. (2016) A Novel Analytical Strategy to Identify Fusion Transcripts between Repetitive Elements and Protein Coding-Exons Using RNA-Seq. PLoS One 11:e0159028
Graziane, Nicholas M; Sun, Shichao; Wright, William J et al. (2016) Opposing mechanisms mediate morphine- and cocaine-induced generation of silent synapses. Nat Neurosci 19:915-25
Khibnik, Lena A; Beaumont, Michael; Doyle, Marie et al. (2016) Stress and Cocaine Trigger Divergent and Cell Type-Specific Regulation of Synaptic Transmission at Single Spines in Nucleus Accumbens. Biol Psychiatry 79:898-905
Kiraly, Drew D; Walker, Deena M; Calipari, Erin S et al. (2016) Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine. Sci Rep 6:35455
Egervari, Gabor; Landry, Joseph; Callens, James et al. (2016) Striatal H3K27 Acetylation Linked to Glutamatergic Gene Dysregulation in Human Heroin Abusers Holds Promise as Therapeutic Target. Biol Psychiatry :

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