The Biostatistics Core (Core B) has been involved in the lithotripsy program project since its inception, providing data management expertise and statistical support to the team of multidisciplinary researchers In assessing the impact of shock wave lithotripsy on renal function and developing new treatment protocols . The specific alms for the Statistics Core for the next five years are:
Aim 1 : Provide statistical support to Investigators of this program project to ensure that appropriate study design and sufficient sample sizes with adequate statistical power are used in all experiments.
Aim 2 : Conduct statistical analyses of experimental data ensuring appropriate statistical models and techniques are used in analyzing each data set. Provide statistical support for accurate presentation of analysis results in reports and publications.
Aim 3 : Develop new statistical methodology to address challenging statistical issues related to both experimental design and data analyses that arise from this research program. The continued involvement of the Biostatistics Core in this research project will ensure that all experiments are conducted with appropriate design and adequate sample size, data are analyzed with appropriate statistical technique, and results are presented accurately with sufficient statistical details.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
5P01DK043881-19
Application #
8484830
Study Section
Special Emphasis Panel (ZDK1-GRB-R)
Project Start
Project End
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
19
Fiscal Year
2013
Total Cost
$100,396
Indirect Cost
$54,922
Name
Indiana University-Purdue University at Indianapolis
Department
Type
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Harper, Jonathan D; Dunmire, Barbrina; Wang, Yak-Nam et al. (2014) Preclinical safety and effectiveness studies of ultrasonic propulsion of kidney stones. Urology 84:484-9
Li, Guangyan; McAteer, James A; Williams Jr, James C et al. (2014) Effect of the body wall on lithotripter shock waves. J Endourol 28:446-52
Connors, Bret A; Evan, Andrew P; Blomgren, Philip M et al. (2014) Comparison of tissue injury from focused ultrasonic propulsion of kidney stones versus extracorporeal shock wave lithotripsy. J Urol 191:235-41
Coralic, Vedran; Colonius, Tim (2014) Finite-volume WENO scheme for viscous compressible multicomponent flows. J Comput Phys 274:95-121
Handa, Rajash K; Evan, Andrew P; Connors, Bret A et al. (2014) Shock wave lithotripsy targeting of the kidney and pancreas does not increase the severity of metabolic syndrome in a porcine model. J Urol 192:1257-65
Hsi, Ryan S; Dunmire, Barbrina; Cunitz, Bryan W et al. (2014) Content and face validation of a curriculum for ultrasonic propulsion of calculi in a human renal model. J Endourol 28:459-63
Alibakhshi, Mohammad A; Kracht, Jonathan M; Cleveland, Robin O et al. (2013) Single-shot measurements of the acoustic field of an electrohydraulic lithotripter using a hydrophone array. J Acoust Soc Am 133:3176-85
Tiwari, Arpit; Freund, Jonathan B; Pantano, Carlos (2013) A Diffuse Interface Model with Immiscibility Preservation. J Comput Phys 252:290-309
Lu, Wei; Sapozhnikov, Oleg A; Bailey, Michael R et al. (2013) Evidence for trapped surface bubbles as the cause for the twinkling artifact in ultrasound imaging. Ultrasound Med Biol 39:1026-38
Coralic, Vedran; Colonius, Tim (2013) Shock-induced collapse of a bubble inside a deformable vessel. Eur J Mech B Fluids 40:64-74

Showing the most recent 10 out of 137 publications