Abstract

Mechanisms of exposure for children's susceptibility are defined by types and frequency of exposures, age-specific behaviors, and temporal and toxicokinetic exposure considerations. The Pesticide Exposure Pathways Research Project focuses on the physical and behavioral mechanisms of children's pesticide exposures. These detailed assessments fit well with the other field and laboratory-based Center projects. The Community-Based Participatory Research Project is evaluating the mechanisms of children 's exposure through occupational takehome and dietary exposures. Their assessments fit well with the detailed spray drift and activity pattern assessments of the Pesticide Exposure Pathways Project. Together, both projects will inform the Exposure Assessment and Risk Characterization Cores and provide a real-life context for the laboratory-based studies. The results of this project will feed back to inform the Community-Based Participatory Research Project and also inform the activities of the Risk Characterization and the Community Outreach and Translation Cores to reduce exposures.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
5P01ES009601-08
Application #
7173277
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
2005-11-01
Budget End
2006-10-31
Support Year
8
Fiscal Year
2006
Total Cost
$96,556
Indirect Cost

  Institution

Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195

  Publications

Ulrich, Angie; Molina, Yamile; Briant, Katherine J et al. (2018) Stress Among Latinos: Does it Vary by Occupation and Agricultural Season? J Occup Environ Med 60:810-814
Griffith, William C; Vigoren, Eric M; Smith, Marissa N et al. (2018) Application of improved approach to evaluate a community intervention to reduce exposure of young children living in farmworker households to organophosphate pesticides. J Expo Sci Environ Epidemiol :
Plascak, Jesse J; Griffith, William C; Workman, Tomomi et al. (2018) Evaluation of the relationship between residential orchard density and dimethyl organophosphate pesticide residues in house dust. J Expo Sci Environ Epidemiol :
Tamaro, Catherine M; Smith, Marissa N; Workman, Tomomi et al. (2018) Characterization of organophosphate pesticides in urine and home environment dust in an agricultural community. Biomarkers 23:174-187
Gibbs, Jenna L; Yost, Michael G; Negrete, Maria et al. (2017) Passive Sampling for Indoor and Outdoor Exposures to Chlorpyrifos, Azinphos-Methyl, and Oxygen Analogs in a Rural Agricultural Community. Environ Health Perspect 125:333-341
Smith, Marissa N; Workman, Tomomi; McDonald, Katie M et al. (2017) Seasonal and occupational trends of five organophosphate pesticides in house dust. J Expo Sci Environ Epidemiol 27:372-378
Stanaway, Ian B; Wallace, James C; Shojaie, Ali et al. (2017) Human Oral Buccal Microbiomes Are Associated with Farmworker Status and Azinphos-Methyl Agricultural Pesticide Exposure. Appl Environ Microbiol 83:
Shaffer, Rachel M; Smith, Marissa N; Faustman, Elaine M (2017) Developing the Regulatory Utility of the Exposome: Mapping Exposures for Risk Assessment through Lifestage Exposome Snapshots (LEnS). Environ Health Perspect 125:085003
Peter, Beate; Wijsman, Ellen M; Nato Jr, Alejandro Q et al. (2016) Genetic Candidate Variants in Two Multigenerational Families with Childhood Apraxia of Speech. PLoS One 11:e0153864
Kim, Hee Yeon; Wegner, Susanna H; Van Ness, Kirk P et al. (2016) Differential epigenetic effects of chlorpyrifos and arsenic in proliferating and differentiating human neural progenitor cells. Reprod Toxicol 65:212-223

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