The overall objective of the Administrative Core is to oversee and coordinate the operations of the Center's activities and foster productive interactions and scientific synergy among the projects and cores within the Center. Additionally, the Administrative Core will coordinate and schedule interactions between the Center and our Community Advisory Council, external organizations such as the California Department of Developmental Services and our External Advisory Board (EAB). The following Objectives encompass the five areas of administrative responsibility: 1). Oversee and coordinate Center activities;2). Facilitate data and resource sharing;3). Provide budgetary oversight and grants management;4). Administer the Center's IRB and liaise with the MARBLES and CHARGE studies for the transfer of samples and data;and 5). Foster interactions and synergy among projects and cores within the Center. Considering the overall complexity of the Center's multidisciplinary approach, the goals of the Administrative Core are designed to provide a central office from which all business, scheduling, and organizational matters can be coordinated, and to facilitate the scientific collaborations among projects and cores that make the CCEH truly interdisciplinary. The Director and Deputy Director, along with the Executive Committee of Program Leaders, provide the day to- day leadership of the CCEH. The EAB provides long-term guidance on scientific and organizational matters. The Administrative Core has established a Community Outreach and Translation Core (COTC) Liaison that will coordinate our administrative efforts with those of our COTC. The COTC contact person (Rose) for the COTC Liaison (Hansen) will relay information regarding matters of public outreach, information exchange, and clinical translation between the two units to assure that these activities are coordinated and that the Director is aware of progress and any problems.

Public Health Relevance

The Administration Core will oversee all aspects of the CCEH to ensure that the overarching theme of the center investigating the molecular and cellular mechanisms by which gene X environment interactions promote neurodevelopmental impairments relevant to autism is successful.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
2P01ES011269-11
Application #
8533672
Study Section
Special Emphasis Panel (ZES1-LKB-K (P0))
Project Start
Project End
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
11
Fiscal Year
2013
Total Cost
$90,193
Indirect Cost
$31,626
Name
University of California Davis
Department
Type
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618
Jones, Karen L; Pride, Michael C; Edmiston, Elizabeth et al. (2018) Autism-specific maternal autoantibodies produce behavioral abnormalities in an endogenous antigen-driven mouse model of autism. Mol Psychiatry :
Rose, Destanie R; Yang, Houa; Serena, Gloria et al. (2018) Differential immune responses and microbiota profiles in children with autism spectrum disorders and co-morbid gastrointestinal symptoms. Brain Behav Immun 70:354-368
Zheng, Jing; Chen, Juan; Zou, Xiaohan et al. (2018) Saikosaponin d causes apoptotic death of cultured neocortical neurons by increasing membrane permeability and elevating intracellular Ca2+ concentration. Neurotoxicology 70:112-121
Shin, Hyeong-Moo; Schmidt, Rebecca J; Tancredi, Daniel et al. (2018) Prenatal exposure to phthalates and autism spectrum disorder in the MARBLES study. Environ Health 17:85
Keil, Kimberly P; Miller, Galen W; Chen, Hao et al. (2018) PCB 95 promotes dendritic growth in primary rat hippocampal neurons via mTOR-dependent mechanisms. Arch Toxicol 92:3163-3173
Zheng, Jing; McKinnie, Shaun M K; El Gamal, Abrahim et al. (2018) Organohalogens Naturally Biosynthesized in Marine Environments and Produced as Disinfection Byproducts Alter Sarco/Endoplasmic Reticulum Ca2+ Dynamics. Environ Sci Technol 52:5469-5478
Chen, Xiaopeng; Walter, Kyla M; Miller, Galen W et al. (2018) Simultaneous quantification of T4, T3, rT3, 3,5-T2 and 3,3'-T2 in larval zebrafish (Danio rerio) as a model to study exposure to polychlorinated biphenyls. Biomed Chromatogr 32:e4185
Jones, Karen L; Van de Water, Judy (2018) Maternal autoantibody related autism: mechanisms and pathways. Mol Psychiatry :
Kerin, Tara; Volk, Heather; Li, Weiyan et al. (2018) Association Between Air Pollution Exposure, Cognitive and Adaptive Function, and ASD Severity Among Children with Autism Spectrum Disorder. J Autism Dev Disord 48:137-150
Miller, Galen W; Chandrasekaran, Vidya; Yaghoobi, Bianca et al. (2018) Opportunities and challenges for using the zebrafish to study neuronal connectivity as an endpoint of developmental neurotoxicity. Neurotoxicology 67:102-111

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