The function of the Administrative Core is to provide administrative support, organization, coordination and efficient management of this Program. Because this Program involves multiple projects, cores, laboratories and investigators, some centralized mechanism to facilitate its smooth operation is absolutely essential. The Administrative Core will be co-directed by Drs. Gregory B. Diette Patrick N. Breysse. Dr. Elizabeth Matsui will support the Program in the role of Pediatric Health Specialist. Dr. Diette also serves as Project Leader of Project 1, while Dr. Breysse leads the Environmental Assessment Core and Dr. Matsui leads Project 2. Together they will be responsible for evaluating the progress and overall administration of the entire Program and its individual projects. The major responsibility of the Administrative Core is to ensure that the combined research and support activities contained in this application marshal their collective efforts to produce a body of science that is greater than the sum of the individual components. The most important function of the Core is to facilitate project and core interaction, coordination, and integration within the mission and theme of the ASTHMA-DIET program. The ASTHMA-DIET key personnel are associated with the Johns Hopkins University Schools of Medicine and Bloomberg School of Public Health Departments of Medicine, Pediatrics, Environmental Health Sciences, Epidemiology, and Biostatistics. The Core will coordinate the inter-project and inter-departmental collaborative arrangements and develop new arrangements as deemed necessary for the scientific progress of the Program as a whole. The Administrative Core will also provide the Projects and Cores with a periodic review of all expenditures and liaise with University Accounting and Grants administrative offices regarding grant budgets. The administrative support provided by the Administrative Core will be responsible for organizing various weekly meetings and seminars as well as the meetings of the Internal and External Advisory Committees and the Community Advisory Board. The overall goals of the Administrative Core are to ensure completion of the proposed research, training and outreach activities, and facilitate interaction and information exchange within and outside the Program.

Public Health Relevance

While asthma is more common and more burdensome in inner city minority children, the reasons for this major health disparity are not completely understood. A diet that is low in fruits, vegetables and dairy, as well as high in meat, junk food and sugary drinks is suspected to increase the vulnerability of children to the effects of airborne allergens and pollutants. Our Center intends to examine the extent to which the poor quality inner city diet may leave children more vulnerable to airborne dust particles, gases and mouse allergen. We expect our findings will lead to practical recommendations to improve the inner city diet.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
5P01ES018176-05
Application #
8528589
Study Section
Special Emphasis Panel (ZES1-LKB-G (P1))
Program Officer
Gray, Kimberly A
Project Start
2009-09-24
Project End
2014-07-31
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
5
Fiscal Year
2013
Total Cost
$741,474
Indirect Cost
$272,442
Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Kim, Jung-Hyun; Thimmulappa, Rajesh K; Kumar, Vineet et al. (2014) NRF2-mediated Notch pathway activation enhances hematopoietic reconstitution following myelosuppressive radiation. J Clin Invest 124:730-41
Kaji, Deepak A; Belli, Andrew J; McCormack, Meredith C et al. (2014) Indoor pollutant exposure is associated with heightened respiratory symptoms in atopic compared to non-atopic individuals with COPD. BMC Pulm Med 14:147
Camargo Jr, Carlos A; Budinger, G R Scott; Escobar, Gabriel J et al. (2014) Promotion of lung health: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases. Ann Am Thorac Soc 11 Suppl 3:S125-38
Okelo, Sande O; Riekert, Kristin A; Eakin, Michelle N et al. (2014) Pediatrician qualifications and asthma management behaviors and their association with patient race/ethnicity. J Asthma 51:155-61
Matsui, E C (2014) Environmental exposures and asthma morbidity in children living in urban neighborhoods. Allergy 69:553-8
Hackstadt, Amber J; Matsui, Elizabeth C; Williams, D'Ann L et al. (2014) Inference for environmental intervention studies using principal stratification. Stat Med 33:4919-33
Little, Frédéric F; Delgado, Diana M; Wexler, Philip J et al. (2014) Salivary inflammatory mediator profiling and correlation to clinical disease markers in asthma. PLoS One 9:e84449
Rivera-Mariani, Felix E; Matsui, Elizabeth C; Breysse, Patrick N (2014) Performance of the halogen immunoassay to assess airborne mouse allergen-containing particles in a laboratory animal facility. J Expo Sci Environ Epidemiol 24:3-8
Sussan, Thomas E; Ingole, Vijendra; Kim, Jung-Hyun et al. (2014) Source of biomass cooking fuel determines pulmonary response to household air pollution. Am J Respir Cell Mol Biol 50:538-48
Soneja, Sutyajeet; Chen, Chen; Tielsch, James M et al. (2014) Humidity and gravimetric equivalency adjustments for nephelometer-based particulate matter measurements of emissions from solid biomass fuel use in cookstoves. Int J Environ Res Public Health 11:6400-16

Showing the most recent 10 out of 33 publications