This Program Project application will employ novel remote sampling technologies to achieve new insights into the population dynamics of known and emerging HAB threats, and to address critical mechanisms of toxin action, linking developmental exposures to adult consequences. The Center will be overseen and guided by the Director and Deputy Director.
The Aims of the Administrative Core are to: 1. Facilitate communication, planning, integration and interaction among Center members, so that the goals and scientific objectives of the Center are achieved. 2. Provide and maintain an administrative structure to oversee and monitor the financial aspects of the Center, including grants management. 3. Establish a structure that will support effective communication and planning with contribution from all Center Investigators, through an Internal Advisory Committee. 4. Establish an External Advisory committee, which will review the Center programs and advise the Director and Deputy Director. 5. Implement evaluation mechanisms, utilizing both Internal and External Advisory Committees. 6. Establish and maintain public and private web pages for the dissemination of information and for data transfer and communication 7. Pursue interactions between the WHCOHH and other OHH Centers, as well as with other EHS Centers, in order to expand the reach and impact of the center, and potentially to engage collaborators on research issues relevant to the Center mission and themes. 8. Encourage the involvement of Center investigators in community outreach and education efforts. 9. Prepare and deliver required reports to the NSF and the NIEHS. 10. Organize COHH meetings as required. 11. Ensure compliance with data submission and archiving policies.

Public Health Relevance

The ultimate mission of the Center is to improve the public health through enhanced understanding of how oceanic and environmental processes affect the production, distribution and persistence of toxin producing organisms, and the risks from exposure to their potent neurotoxins. The Administrative Core will oversee the functions of the Center to ensure objectives are achieved, to the benefit of society.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Research Program Projects (P01)
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Special Emphasis Panel (ZES1-LKB-J)
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Woods Hole Oceanographic Institution
Woods Hole
United States
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Fernandes, Luciano F; Hubbard, Katherine A; Richlen, Mindy L et al. (2014) Diversity and toxicity of the diatom Pseudo-nitzschia Peragallo in the Gulf of Maine, Northwestern Atlantic Ocean. Deep Sea Res Part 2 Top Stud Oceanogr 103:139-162
Butman, Bradford; Aretxabaleta, Alfredo L; Dickhudt, Patrick J et al. (2014) Investigating the importance of sediment resuspension in Alexandrium fundyense cyst population dynamics in the Gulf of Maine. Deep Sea Res Part 2 Top Stud Oceanogr 103:79-95
Pilskaln, C H; Hayashi, K; Keafer, B A et al. (2014) Benthic nepheloid layers in the Gulf of Maine and Alexandrium cyst inventories. Deep Sea Res Part 2 Top Stud Oceanogr 103:55-65
Brosnahan, Michael L; Farzan, Shahla; Keafer, Bruce A et al. (2014) Complexities of bloom dynamics in the toxic dinoflagellate Alexandrium fundyense revealed through DNA measurements by imaging flow cytometry coupled with species-specific rRNA probes. Deep Sea Res Part 2 Top Stud Oceanogr 103:185-198
Koch, F; Kang, Y; Villareal, T A et al. (2014) A novel immunofluorescence flow cytometry technique detects the expansion of brown tides caused by Aureoumbra lagunensis to the Caribbean Sea. Appl Environ Microbiol 80:4947-57
Anderson, Donald M; Keafer, Bruce A; Kleindinst, Judith L et al. (2014) Alexandrium fundyense cysts in the Gulf of Maine: long-term time series of abundance and distribution, and linkages to past and future blooms. Deep Sea Res Part 2 Top Stud Oceanogr 103:6-26
Anderson, Donald M; Couture, Darcie A; Kleindinst, Judith L et al. (2014) Understanding interannual, decadal level variability in paralytic shellfish poisoning toxicity in the Gulf of Maine: the HAB Index. Deep Sea Res Part 2 Top Stud Oceanogr 103:264-276
Kleindinst, Judith L; Anderson, Donald M; McGillicuddy Jr, Dennis J et al. (2014) Categorizing the severity of paralytic shellfish poisoning outbreaks in the Gulf of Maine for forecasting and management. Deep Sea Res Part 2 Top Stud Oceanogr 103:277-287
Deeds, Jonathan R; Petitpas, Christian M; Shue, Vangie et al. (2014) PSP toxin levels and plankton community composition and abundance in size-fractionated vertical profiles during spring/summer blooms of the toxic dinoflagellate Alexandrium fundyense in the Gulf of Maine and on Georges Bank, 2007, 2008, and 2010: 1. Toxin Deep Sea Res Part 2 Top Stud Oceanogr 103:329-349
McGillicuddy Jr, D J; Brosnahan, M L; Couture, D A et al. (2014) A red tide of Alexandrium fundyense in the Gulf of Maine. Deep Sea Res Part 2 Top Stud Oceanogr 103:174-184

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