The overall goal of the Administrative Core is to provide infrastructure and oversight to maximize NICHES scientific success. The Director, Susan K, Murphy, PhD, the Center's Child Health Specialist, Scott Kollins, PhD, and the Program Administrator, Ms. Dale Montana will work together closely within the Administrative Core to coordinate Center operations. They will be supported in this role by an External Advisory Committee (EAC) and by an Executive Committee (EC), which consists of the key investigators participating in the Community Outreach and Translation Core (COTC) and the Research Projects. The Administrative Core has the following Specific Aims: 1) Foster and maintain communication among team members, with the EAC, with the NIEHS and EPA, and with other Children's Centers;2) Organize and integrate NICHES research, investigator training, and outreach activities to promote synergy and maximize the Center's impact on children's health in the community;3) Promote the training of experts in cross-disciplinary fields in children's environmental health;4) Manage fiscal and other resources;and 5) Track NICHES outputs and outcomes to ensure timely progress towards center goals.

Public Health Relevance

The Administrative Core will provide the infrastructure required to enable NICHES to effectively carry out its research objectives and translate scientific discoveries through education and clinical application. The Administrative Core will facilitate integration of the projects and community outreach efforts by leveraging unique resources at Duke in order improve the health of children and future generations.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Research Program Projects (P01)
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Special Emphasis Panel (ZES1-LKB-K)
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Duke University
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Slotkin, Theodore A; Card, Jennifer; Stadler, Ashley et al. (2014) Effects of tobacco smoke on PC12 cell neurodifferentiation are distinct from those of nicotine or benzo[a]pyrene. Neurotoxicol Teratol 43:19-24
Murphy, Susan K (2014) Obesity: Paternal obesity--a risk factor for autism? Nat Rev Endocrinol 10:389-90
Slotkin, Theodore A; Card, Jennifer; Seidler, Frederic J (2014) Nicotine administration in adolescence reprograms the subsequent response to nicotine treatment and withdrawal in adulthood: sex-selective effects on cerebrocortical serotonergic function. Brain Res Bull 102:1-8
Soubry, Adelheid; Hoyo, Cathrine; Jirtle, Randy L et al. (2014) A paternal environmental legacy: evidence for epigenetic inheritance through the male germ line. Bioessays 36:359-71
Nye, Monica D; Fry, Rebecca C; Hoyo, Cathrine et al. (2014) Investigating Epigenetic Effects of Prenatal Exposure to Toxic Metals in Newborns: Challenges and Benefits. Med Epigenet 2:53-59