Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
5P01GM022778-38
Application #
8450795
Study Section
Special Emphasis Panel (ZRG1-BCMB-K)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
38
Fiscal Year
2013
Total Cost
$188,435
Indirect Cost
$74,579
Name
Yale University
Department
Type
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Warkentin, Matthew; Hopkins, Jesse B; Haber, Jonah B et al. (2014) Temperature-dependent radiation sensitivity and order of 70S ribosome crystals. Acta Crystallogr D Biol Crystallogr 70:2890-6
Wang, Jimin; Wing, Richard A (2014) Diamonds in the rough: a strong case for the inclusion of weak-intensity X-ray diffraction data. Acta Crystallogr D Biol Crystallogr 70:1491-7
Roth, Adam; Weinberg, Zasha; Chen, Andy G Y et al. (2014) A widespread self-cleaving ribozyme class is revealed by bioinformatics. Nat Chem Biol 10:56-60
Wang, Jimin; Li, Yue; Modis, Yorgo (2014) Exploiting subtle structural differences in heavy-atom derivatives for experimental phasing. Acta Crystallogr D Biol Crystallogr 70:1873-83
McCown, Phillip J; Liang, Jonathan J; Weinberg, Zasha et al. (2014) Structural, functional, and taxonomic diversity of three preQ1 riboswitch classes. Chem Biol 21:880-9
Polikanov, Yury S; Steitz, Thomas A; Innis, C Axel (2014) A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome. Nat Struct Mol Biol 21:787-93
Askerka, Mikhail; Wang, Jimin; Brudvig, Gary W et al. (2014) Structural changes in the oxygen-evolving complex of photosystem II induced by the S1 to S2 transition: A combined XRD and QM/MM study. Biochemistry 53:6860-2
Polikanov, Yury S; Szal, Teresa; Jiang, Fuyan et al. (2014) Negamycin interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA. Mol Cell 56:541-50
Wang, Jimin; Li, Yue; Modis, Yorgo (2014) Structural models of the membrane anchors of envelope glycoproteins E1 and E2 from pestiviruses. Virology 454-455:93-101
Nelson, James W; Sudarsan, Narasimhan; Furukawa, Kazuhiro et al. (2013) Riboswitches in eubacteria sense the second messenger c-di-AMP. Nat Chem Biol 9:834-9

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