The Administration Core is responsible the overall direction and coordination of the research projects, evaluation of research progress, and for the overall and day-to-day administration of the Program. The core director will monitor progress via regular research meetings of program directors and research personnel. The core will also coordinate and schedule journal clubs, research meetings, seminar program, and research retreats. The core is directed by Dr. Michael Ostap, who is director of the PMI. Dr. Ostap has administrative resources provided by the University of Pennsylvania to help support the mission of the core.
Specific Aims are (1) to oversee and coordinate the project mission, monitor progress, and establish timelines, and (2) develop, coordinate, and schedule research meetings, journal clubs, symposia, retreats, and visiting scientists programs that are critical to our research mission.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
2P01GM087253-11
Application #
8742370
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-07-31
Support Year
11
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
McIntosh, Betsy B; Pyrpassopoulos, Serapion; Holzbaur, Erika L F et al. (2018) Opposing Kinesin and Myosin-I Motors Drive Membrane Deformation and Tubulation along Engineered Cytoskeletal Networks. Curr Biol 28:236-248.e5
Moore, Andrew S; Holzbaur, Erika L F (2018) Mitochondrial-cytoskeletal interactions: dynamic associations that facilitate network function and remodeling. Curr Opin Physiol 3:94-100
Woody, Michael S; Capitanio, Marco; Ostap, E Michael et al. (2018) Electro-optic deflectors deliver advantages over acousto-optical deflectors in a high resolution, ultra-fast force-clamp optical trap. Opt Express 26:11181-11193
Lee, In-Gyun; Olenick, Mara A; Boczkowska, Malgorzata et al. (2018) A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity. Nat Commun 9:986
Hendricks, Adam G; Goldman, Yale E (2017) Measuring Molecular Forces Using Calibrated Optical Tweezers in Living Cells. Methods Mol Biol 1486:537-552
Kast, David J; Dominguez, Roberto (2017) The Cytoskeleton-Autophagy Connection. Curr Biol 27:R318-R326
Lippert, Lisa G; Dadosh, Tali; Hadden, Jodi A et al. (2017) Angular measurements of the dynein ring reveal a stepping mechanism dependent on a flexible stalk. Proc Natl Acad Sci U S A 114:E4564-E4573
Pyrpassopoulos, Serapion; Shuman, Henry; Ostap, E Michael (2017) Adhesion force and attachment lifetime of the KIF16B-PX domain interaction with lipid membranes. Mol Biol Cell 28:3315-3322
Lewis, John H; Jamiolkowski, Ryan M; Woody, Michael S et al. (2017) Deconvolution of Camera Instrument Response Functions. Biophys J 112:1214-1220
Greenberg, Michael J; Shuman, Henry; Ostap, E Michael (2017) Measuring the Kinetic and Mechanical Properties of Non-processive Myosins Using Optical Tweezers. Methods Mol Biol 1486:483-509

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