Abstract

The Histology Core will function to provide extensive services to each of the five projects. The Core Facility will be used in 4 ways. First, it will optimize staining protocols for antibodies used for evaluation of specific markers in sections from brain, slice cultures and dissociated cultures. Second, it will provide sectioning (paraffin or cryostat). Third, it will perform immunohistochemisty. Fourth, it will provide quantitative stereological services to projects. Thus, it will host a complete range of services for all projects, with oversight by the Pis and technical support staff to standardize procedures and maintain quality control. This will result in significant savings in terms of immunohistochemical supplies and in tissue preparation and sectioning.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
7P01HD023315-26
Application #
8733296
Study Section
Special Emphasis Panel (ZHD1-MCHG-B (DC))
Project Start
2013-07-03
Project End
2014-06-30
Budget Start
2013-07-03
Budget End
2014-06-30
Support Year
26
Fiscal Year
2013
Total Cost
$70,292
Indirect Cost
$25,721

  Institution

Name
Rbhs-Robert Wood Johnson Medical School
Department
Type
DUNS #
078795875
City
Piscataway
State
NJ
Country
United States
Zip Code
08854

  Publications

Sheleg, M; Yu, Q; Go, C et al. (2017) Decreased maternal behavior and anxiety in ephrin-A5-/- mice. Genes Brain Behav 16:271-284
Bowling, Heather; Bhattacharya, Aditi; Klann, Eric et al. (2016) Deconstructing brain-derived neurotrophic factor actions in adult brain circuits to bridge an existing informational gap in neuro-cell biology. Neural Regen Res 11:363-7
Huang, Yangyang; Dreyfus, Cheryl F (2016) The role of growth factors as a therapeutic approach to demyelinating disease. Exp Neurol 283:531-40
Lee, Hee Jae; Dreyfus, Cheryl; DiCicco-Bloom, Emanuel (2016) Valproic acid stimulates proliferation of glial precursors during cortical gliogenesis in developing rat. Dev Neurobiol 76:780-98
Bowling, Heather; Bhattacharya, Aditi; Zhang, Guoan et al. (2016) BONLAC: A combinatorial proteomic technique to measure stimulus-induced translational profiles in brain slices. Neuropharmacology 100:76-89
Mony, Tamanna Jahan; Lee, Jae Won; Dreyfus, Cheryl et al. (2016) Valproic Acid Exposure during Early Postnatal Gliogenesis Leads to Autistic-like Behaviors in Rats. Clin Psychopharmacol Neurosci 14:338-344
Das, Gitanjali; Yu, Qili; Hui, Ryan et al. (2016) EphA5 and EphA6: regulation of neuronal and spine morphology. Cell Biosci 6:48
Ma, Qian; Yang, Jianmin; Li, Thomas et al. (2015) Selective reduction of striatal mature BDNF without induction of proBDNF in the zQ175 mouse model of Huntington's disease. Neurobiol Dis 82:466-477
Anastasia, Agustin; Barker, Phillip A; Chao, Moses V et al. (2015) Detection of p75NTR Trimers: Implications for Receptor Stoichiometry and Activation. J Neurosci 35:11911-20
Sheleg, Michal; Yochum, Carrie L; Richardson, Jason R et al. (2015) Ephrin-A5 regulates inter-male aggression in mice. Behav Brain Res 286:300-7

Showing the most recent 10 out of 187 publications