The PPG is committed to a tightly integrated, cross-disciplinary design, bringing multiple levels of analysis and techniques to bear on shared specific themes in linking social phenotype to brain to gene. An overarching goal for the PPG is to create a framework to link each Project with the others. Core B is at the heart of this function, ensuring that, to the extent possible, participants are investigated by each of the disciplines represented by the different Projects. Core B, based at The Salk Institute's Laboratory for Cognitive Neuroscience (LCN), with Dr. Ursula Bellugi serving as Principal Investigator, is an efficient model for achieving this goal through its provision of a central infrastructure for the following services: (i)Planning and executing outreach activities that establish and maintain connections with the target participant communities (WS, DD) through referral sources as well as local, national, and international organizations;(ii)ldentifying and recruiting potential participants;(iii) Performing the induction screening, administering and scoring the Core Diagnostic Battery, and gathering medical and background information necessary for the application of inclusionary/exclusionary criteria;(iv) Administering and scoring a Core Cognitive Battery;(v) Coordinating an efficient schedule of participation across Projects;(vi) Tracking and ensuring the participation of all subjects across Projects;(vii) Coordinating the acquisition, transport, and collection of human tissue samples (e.g., blood samples for Project I;dental pulp for Project 11;brain tissue for Project 111). Overall, Core B centralizes the participant recruitment efforts and oversees participant tracking and participation inappropriate Projects.

Public Health Relevance

; One of the NICHD missions is research that leads to increased understanding and treatment of social behavior and emotional disorders. Relatively little research has targeted the study of genes to neural circuits to social behavior, uniti our PPG studies. Bore B is instrumental in laying out the foundation (by recruiting subjects and centralizing the data collected by all projects) for such an interdisciplinary program.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
5P01HD033113-18
Application #
8625797
Study Section
Special Emphasis Panel (ZHD1-MRG-C)
Project Start
Project End
Budget Start
2014-03-01
Budget End
2015-02-28
Support Year
18
Fiscal Year
2014
Total Cost
$77,579
Indirect Cost
$28,641
Name
University of Utah
Department
Type
DUNS #
009095365
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
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