The objective of the Administrative Core is to provide comprehensive administrative support to the Program Project grant """"""""Prenatal Programming of Reproductive Health and Disease"""""""" consistent with NICHD POI Research"""""""" guidelines. University of Michigan policy, and applicable State and Federal regulations. The Administrative Core will: 1) foster and coordinate communication amongst members of the Program Project, between projects and other research programs. Centers and Institutes in the University;2) maintain communication with and writing reports to granting agency;3) aid in sustaining scientific momentum, maintaining the quality of research performed, and ensure timely publications of findings;4) ensure quality control;5) organize the Steering Committee meetings;6) plan and arrange the annual External Committee meeting;and 7) maintain minutes of the Steering and the External Committee meetings. The Administrative Core will manage the Program Project budget and consult with steering committee as needed to assure that Program Project and Core budgets are efficiently utilized and scientific progress is maintained.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Research Program Projects (P01)
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Special Emphasis Panel (ZHD1-DSR-L)
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University of Michigan Ann Arbor
Ann Arbor
United States
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Veiga-Lopez, A; Moeller, J; Abbott, D H et al. (2016) Developmental programming: rescuing disruptions in preovulatory follicle growth and steroidogenesis from prenatal testosterone disruption. J Ovarian Res 9:39
Cernea, Maria; Phillips, Rebecca; Padmanabhan, Vasantha et al. (2016) Prenatal testosterone exposure decreases colocalization of insulin receptors in kisspeptin/neurokinin B/dynorphin and agouti-related peptide neurons of the adult ewe. Eur J Neurosci 44:2557-2568
Padmanabhan, Vasantha; Cardoso, Rodolfo C; Puttabyatappa, Muraly (2016) Developmental Programming, a Pathway to Disease. Endocrinology 157:1328-40
Puttabyatappa, Muraly; Cardoso, Rodolfo C; Padmanabhan, Vasantha (2016) Effect of maternal PCOS and PCOS-like phenotype on the offspring's health. Mol Cell Endocrinol 435:29-39
Cardoso, Rodolfo C; Burns, Ashleigh; Moeller, Jacob et al. (2016) Developmental Programming: Insulin Sensitizer Prevents the GnRH-Stimulated LH Hypersecretion in a Sheep Model of PCOS. Endocrinology 157:4641-4653
Cardoso, Rodolfo C; Veiga-Lopez, Almudena; Moeller, Jacob et al. (2016) Developmental Programming: Impact of Gestational Steroid and Metabolic Milieus on Adiposity and Insulin Sensitivity in Prenatal Testosterone-Treated Female Sheep. Endocrinology 157:522-35
Lu, Chunxia; Cardoso, Rodolfo C; Puttabyatappa, Muraly et al. (2016) Developmental Programming: Prenatal Testosterone Excess and Insulin Signaling Disruptions in Female Sheep. Biol Reprod 94:113
Puttabyatappa, Muraly; Cardoso, Rodolfo C; Herkimer, Carol et al. (2016) Developmental programming: postnatal estradiol modulation of prenatally organized reproductive neuroendocrine function in sheep. Reproduction 152:139-50
Vyas, Arpita K; Hoang, Vanessa; Padmanabhan, Vasantha et al. (2016) Prenatal programming: adverse cardiac programming by gestational testosterone excess. Sci Rep 6:28335
Padmanabhan, Vasantha; Veiga-Lopez, Almudena; Herkimer, Carol et al. (2015) Developmental Programming: Prenatal and Postnatal Androgen Antagonist and Insulin Sensitizer Interventions Prevent Advancement of Puberty and Improve LH Surge Dynamics in Prenatal Testosterone-Treated Sheep. Endocrinology 156:2678-92

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