A fundamental issue in cognitive neuroscience is how the brain is able to encode others'actions and intentions. In this perspective one of the most important advances of our knowledge on how these processes can take place in the cortex is the discovery of mirror neurons. The main conceptual breakthrough open by their discovery is that perceptual and motor processes share a common code. The proposed research will investigate, with non-invasive electroencephalography methods, the emergence of the MN system in infancy and young children. It will compare the EEG activity depicted by specific frequency bands in infants with that of children and adults in which the MNs has been widely studied. Acquisition of EEG will be combined with a careful behavioral assessment of subjects in order to test the hypothesis that MNs are at the basis of specific matching behaviors that are important landmarks in the development of perception action relations. We will as well, carry out experiments in non-human primates to identify these EEG rhythms in infant Rhesus Macaque and to link, for the first time, single cell recordings of mirror neurons to the ongoing EEG.
The study of the MNs development is largely unexplored. Here we propose to investigate the emergence of this system in relation to important behavioural-cognitive skills by means of neurophysiological measurements. The findings will be central for understanding the neural mechanisms underlying action understanding and imitation, which are fundamental elements of social cognitive development.
|Yoo, Kathryn H; Cannon, Erin N; Thorpe, Samuel G et al. (2016) Desynchronization in EEG during perception of means-end actions and relations with infants' grasping skill. Br J Dev Psychol 34:24-37|
|Dettmer, Amanda M; Kaburu, Stefano S K; Byers, Kristen L et al. (2016) First-time rhesus monkey mothers, and mothers of sons, preferentially engage in face-to-face interactions with their infants. Am J Primatol 78:238-46|
|Tramacere, Antonella; Pievani, Telmo; Ferrari, Pier F (2016) Mirror neurons in the tree of life: mosaic evolution, plasticity and exaptation of sensorimotor matching responses. Biol Rev Camb Philos Soc :|
|Simpson, Elizabeth A; Nicolini, Ylenia; Shetler, Melissa et al. (2016) Experience-independent sex differences in newborn macaques: Females are more social than males. Sci Rep 6:19669|
|Simpson, Elizabeth A; Miller, Grace M; Ferrari, Pier F et al. (2016) Neonatal imitation and early social experience predict gaze following abilities in infant monkeys. Sci Rep 6:20233|
|Fox, Nathan A; Bakermans-Kranenburg, Marian J; Yoo, Kathryn H et al. (2016) Assessing human mirror activity with EEG mu rhythm: A meta-analysis. Psychol Bull 142:291-313|
|Kaburu, Stefano S K; Paukner, Annika; Simpson, Elizabeth A et al. (2016) Neonatal imitation predicts infant rhesus macaque (Macaca mulatta) social and anxiety-related behaviours at one year. Sci Rep 6:34997|
|Jakobsen, Krisztina V; Umstead, Lindsey; Simpson, Elizabeth A (2016) Efficient human face detection in infancy. Dev Psychobiol 58:129-36|
|Cannon, Erin N; Simpson, Elizabeth A; Fox, Nathan A et al. (2016) Relations between infants' emerging reach-grasp competence and event-related desynchronization in EEG. Dev Sci 19:50-62|
|CoudÃ©, Gino; Festante, Fabrizia; Cilia, Adriana et al. (2016) Mirror Neurons of Ventral Premotor Cortex Are Modulated by Social Cues Provided by Others' Gaze. J Neurosci 36:3145-56|
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