RISK GENES AND ENVIRONMENT INTERACTIONS IN NTDS ADMINISTRATIVE CORE Core A will provide an anchor for the Program, assisting in grant administration and budget management as well as preparation of annual reports. It will organize annual meetings of the Internal and External Advisory committees with Program investigators. Annual Internal Advisory Board meetings will take place in Manhattan, while yearly External Advisory Board meetings will take place alternately in NY or TX. The Core will continue to schedule the monthly meetings of the project participants, which take place via videoconferencing. It will organize and administratively support the periodic meetings in NY and TX of Program investigators. Core A will coordinate training opportunities for Program investigators (students, postdocs, faculty). It will support collaborative experiments across Projects by facilitating the shipment of materials between NY and TX. It will serve as the administrative link between the Cornell University Life Sciences Core (CLC) facility and the laboratories at WCMC in New York, and in Texas, at TMHRI and the University of Texas at Austin, Dell Pediatric Research Institute.

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National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Research Program Projects (P01)
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Special Emphasis Panel (ZHD1-DSR-N)
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Weill Medical College of Cornell University
New York
United States
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Hansler, Alex; Chen, Qiuying; Ma, Yuliang et al. (2016) Untargeted metabolite profiling reveals that nitric oxide bioynthesis is an endogenous modulator of carotenoid biosynthesis in Deinococcus radiodurans and is required for extreme ionizing radiation resistance. Arch Biochem Biophys 589:38-52
Akimova, Darya; Wlodarczyk, Bogdan J; Lin, Ying et al. (2016) Metabolite profiling of whole murine embryos reveals metabolic perturbations associated with maternal valproate-induced neural tube closure defects. Birth Defects Res A Clin Mol Teratol :
Denny, Kerina J; Kelly, Christina F; Kumar, Vinod et al. (2016) Autoantibodies against homocysteinylated protein in a mouse model of folate deficiency-induced neural tube defects. Birth Defects Res A Clin Mol Teratol 106:201-7
Ross, M Elizabeth; Mason, Christopher E; Finnell, Richard H (2016) Genomic approaches to the assessment of human spina bifida risk. Birth Defects Res A Clin Mol Teratol :
Chen, Xiaoli; An, Yu; Gao, Yonghui et al. (2016) Rare Deleterious PARD3 Variants in the aPKC-Binding Region are Implicated in the Pathogenesis of Human Cranial Neural Tube Defects via Disrupting Apical Tight Junction Formation. Hum Mutat :
Mitchell, Emma; Klein, Shifra L; Argyropoulos, Kimon V et al. (2016) Behavioural traits propagate across generations via segregated iterative-somatic and gametic epigenetic mechanisms. Nat Commun 7:11492
Lei, Yunping; Finnell, Richard H (2016) New Techniques for the Study of Neural Tube Defects. Adv Tech Biol Med 4:
Shawlot, William; Vazquez-Chantada, Mercedes; Wallingford, John B et al. (2015) Rfx2 is required for spermatogenesis in the mouse. Genesis :
Lei, Yunping; Fathe, Kristin; McCartney, Danielle et al. (2015) Rare LRP6 variants identified in spina bifida patients. Hum Mutat 36:342-9
Cantarel, Brandi L; Lei, Yunping; Weaver, Daniel et al. (2015) Analysis of archived residual newborn screening blood spots after whole genome amplification. BMC Genomics 16:602

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