The goals of the Morphology Core are to provide professional services and expertise to investigators of the Integrative Neurobiology of Cardiovascular Regulation Program Project. To facilitate these goals the Morphology Core will provide 1) technical assistance for labor intensive histotechnology techniques from tissue processing to specialized staining, 2) professional veterinary pathology support for gross, microscopic and anatomic phenotyping, 3) economic benefits througti centralization of equipment, experienced professional staff and availability of specialized histochemical/immunohistochemical reagents, and 4) consultation and instruction in specialized morphologic techniques and image analysis. Program Investigators will have full access to the Core's expertise and resources. The Morphology Core will provide its services to Program Investigators in a timely and efficient manner for optimal assessment of tissues.
The Specific Aims of the Morphology Core are: 1) Provide scientific support, expertise and technical labor for microscopic slide processing from tissues, routine to specialized application of histochemical stains, and immunohistochemistry techniques. 2) Provide expertise and resources to develop new morphologic or morphometric techniques as required to facilitate the needs of Project Investigators. 3) Provide veterinary pathology support (through boarded veterinary pathologists) for examination and interpretation of gross to microscopic tissues and for consultation in experimental design. 4) Provide expertise and a uniform framework for the standardized assessment of tissues collected by Project Investigators to define a comprehensive anatomic assessment/phenotype of PPG models and experiments.
The goal of the Morphology Core is to provide professional services and expertise to Investigators of the Program Project Grant.
|Xue, Baojian; Thunhorst, Robert L; Yu, Yang et al. (2016) Central Renin-Angiotensin System Activation and Inflammation Induced by High-Fat Diet Sensitize Angiotensin II-Elicited Hypertension. Hypertension 67:163-70|
|Pierce, Gary L; Kalil, Graziela Z; Ajibewa, Tiwaloluwa et al. (2016) Anxiety independently contributes to elevated inflammation in humans with obesity. Obesity (Silver Spring) :|
|Chu, Yi; Lund, Donald D; Doshi, Hardik et al. (2016) Fibrotic Aortic Valve Stenosis in Hypercholesterolemic/Hypertensive Mice. Arterioscler Thromb Vasc Biol 36:466-74|
|Littlejohn, Nicole K; Keen, Henry L; Weidemann, Benjamin J et al. (2016) Suppression of Resting Metabolism by the Angiotensin AT2 Receptor. Cell Rep 16:1548-60|
|Pierce, G L; Harris, S A; Seals, D R et al. (2016) Estimated aortic stiffness is independently associated with cardiac baroreflex sensitivity in humans: role of ageing and habitual endurance exercise. J Hum Hypertens 30:513-20|
|Harwani, Sailesh C; Ratcliff, Jason; Sutterwala, Fayyaz S et al. (2016) Nicotine Mediates CD161a+ Renal Macrophage Infiltration and Premature Hypertension in the Spontaneously Hypertensive Rat. Circ Res 119:1101-1115|
|Chapleau, Mark W; Rotella, Diane L; Reho, John J et al. (2016) Chronic vagal nerve stimulation prevents high-salt diet-induced endothelial dysfunction and aortic stiffening in stroke-prone spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 311:H276-85|
|Fiedorowicz, Jess G; Dantz, Bezalel; Blazek, Mary C (2016) Attitudes and Confidence in the Integration of Psychiatry Scale. Acad Psychiatry 40:218-23|
|Sabharwal, Rasna; Rasmussen, Lynn; Sluka, Kathleen A et al. (2016) Exercise prevents development of autonomic dysregulation and hyperalgesia in a mouse model of chronic muscle pain. Pain 157:387-98|
|Xue, Baojian; Yu, Yang; Zhang, Zhongming et al. (2016) Leptin Mediates High-Fat Diet Sensitization of Angiotensin II-Elicited Hypertension by Upregulating the Brain Renin-Angiotensin System and Inflammation. Hypertension 67:970-6|
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