A.ADMINISTRATION. The Program Project Grant Director, Dr. Segrest, is Director of the AtherosclerosisResearch Unit (ARU), the administrative home for the program project. He also is Director of the Center forComputational and Structural Biology at UAB. He will be responsible for planning of the overall direction of theprogram and for quality control. One of the major roles of the Director will be to foster interactions and to stimulatenew ideas and directions within and between the various projects and core units.Systems management support and programming support for the Program Project will be provided by MartinJones, MS. Mr. Jones manages the computing section of the ARU and assists investigators with programmingsolutions. He also provides assistance in troubleshooting, pricing, and computer replacement/upgrading.He is also currently working on two research problems: i) He is updating the 'Wheel Programs' suite(consisting of the programs Locate, Wheel, Helnet, and Combo) to use a more portable and usable interface.He is also working to make these programs more readily available. (See www.aru.uab.edu/resources.html) ii) He is working with Dr. Gilbert Weinstein of the Department of Mathematics at UAB tocomputationally model the dynamic physical and differential geometric evolution of HDL-like disc particles.Most of the clerical and desktop publishing services, correspondence, etc. will be provided by LaDonnaBangham. She will prepare and submit purchase orders, track expenditures, and make the travel arrangementsfor the program faculty. She provides support for faculty and staff involved in all aspects of the PPG.Ms. Bangham will be responsible for coordination of the travel arrangements for the PPG External advisoryCommittee and external speakers for the ARU Scientific Seminars.An ARU Internal Advisory Committee, independent of the program project investigators, provides periodicscientific and administrative advice to the Director of the program project/ARU. The PPG Internal AdvisoryCommittee will meet monthly to provide information and advice to the Director.The PPG External Advisory Committee will consist of four extramural scientists to be appointed to overlappingthree year terms who will perform a site visit yearly to review individual components of the programproject for the Director.B.COMPUTATIONShared high performance computingfacility used by this PPG.The primary computational resourcefor Project 1 of this PPG is a singlerack UAB Blue Gene. The UAB BlueGene, an IBM Blue Gene/L, is auniquely designed massively parallelsupercomputer. A single Blue Gene/L rack has 1024 nodes, each nodehaving two processors and 512MBof main memory. The 2048 processorsin the Blue Gene/L rack aretightly integrated in one form factorusing five proprietary high-speedinterconnection networks, producinga peak performance of 5.6 Teraflops.There are 13 Terabytes of disk storageavailable to this cluster. TheSegrest group is currently scheduled for 50% minimum usage of the UAB Blue Gene, with on-demand utilizationof 100% of the 2048 processors of the UAB Blue Gene.Secondary Computing resources are provided by three commodity clusters.Coosa: A DELL Xeon 64-bit Linux HPC Cluster that consists of a 128-node DELL PE1425 computer that hasdual Xeon 3.6GHz processors with either 2GB or 6GB of memory per node. There are 4 Terabytes of diskstorage available to this cluster. This cluster is rated at more than 1 Teraflops computing capacityCheaha: A Verari Opteron 64-bit Linux HPC Cluster that consists of a 64-node dual AMD Opteron 242 computerwith 2GB of memory each node.Both Coosa and Cheaha clusters use Gigabit Ethernet inter-node network connections.Olympus: A 128-node (256- processor), 1.4Teraflop-rated grid node that is similar to CoosaThe Coosa and Cheaha clusters, as well as the DAB Blue Gene, are supported by Dr. Bharat Soni's group inthe School of Engineering. Olympus support is provided Dr. Tony Skjellum's department - Computer andInformation Sciences. The Segrest research group is flexibly scheduled for 264 (64-bit) cpu from these clustersat any one time.
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