Abstract

The Biostatistics and Genetic Epidemiology Core combines the experience and resources of the Departments of Biostatistics and Biomathematics, and the Biostatistics Consulting Center at UCLA, with the Division of Medical Genetics at Cedars-Sinai Medical Center. The general aim is to support the projects in this Program Project Grant in these specific ways: 1. Assist the development of the study design for each project; 2. Collect and manage all phenotypic and genetic data from the projects, including computerized data entry, data editing; 3. Develop the specific database management systems for each project; 4. Develop a database management system for the entire Program Project Grant; 5. Prepare timely reports on the progress of each project with collaboration from the project P.I.s and the Administrative Core; 6. Develop protocols for the data analysis to be carried out and carry out such analyses; 7. Prepare the Operations Manual for the program, including all issues raised in 1-6 above; 8. Assist in the preparation of the manuscripts for publication and presentation.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
1P01HL060030-01A1
Application #
6189150
Study Section
Project Start
1999-08-01
Project End
2000-07-31
Budget Start
Budget End
Support Year
1
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Type
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Jo Hodonsky, Chani; Schurmann, Claudia; Schick, Ursula M et al. (2018) Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study. Am J Hematol :
Kerr, Kathleen F; Avery, Christy L; Lin, Henry J et al. (2017) Genome-wide association study of heart rate and its variability in Hispanic/Latino cohorts. Heart Rhythm 14:1675-1684
Kuo, Jane Z; Wong, Tien Y; Rotter, Jerome I (2014) Challenges in elucidating the genetics of diabetic retinopathy. JAMA Ophthalmol 132:96-107
Ranganathan, Gouri; Unal, Resat; Pokrovskaya, Irina D et al. (2012) The lipoprotein lipase (LPL) S447X gain of function variant involves increased mRNA translation. Atherosclerosis 221:143-7
Langfelder, Peter; Castellani, Lawrence W; Zhou, Zhiqiang et al. (2012) A systems genetic analysis of high density lipoprotein metabolism and network preservation across mouse models. Biochim Biophys Acta 1821:435-47
Goodarzi, Mark O; Lehman, Donna M; Taylor, Kent D et al. (2007) SORCS1: a novel human type 2 diabetes susceptibility gene suggested by the mouse. Diabetes 56:1922-9
Davis, Richard C; Jin, Angela; Rosales, Melenie et al. (2007) A genome-wide set of congenic mouse strains derived from CAST/Ei on a C57BL/6 background. Genomics 90:306-13
Li, Xiaohui; Quinones, Manuel J; Wang, Dai et al. (2006) Genetic effects on obesity assessed by bivariate genome scan: the Mexican-American coronary artery disease study. Obesity (Silver Spring) 14:1192-200
Estrada-Smith, Daria; Collins, Alan R; Wang, Xuping et al. (2006) Impact of chromosome 2 obesity loci on cardiovascular complications of insulin resistance in LDL receptor-deficient C57BL/6 mice. Diabetes 55:2265-71
Goodarzi, Mark O; Quinones, Manuel J; Azziz, Ricardo et al. (2005) Polycystic ovary syndrome in Mexican-Americans: prevalence and association with the severity of insulin resistance. Fertil Steril 84:766-9

Showing the most recent 10 out of 32 publications