The project is administered by the PI, the Program Administrator, Ms. Tolise Miles with the assistance of the Program Coordinator, Ms. Wing Kam Emily Chan. They provide the routine and strategic management for the administration of the Core. They oversee the finances of the project. The Core provides the interface between the scientific investigators and the purchasing, regulatory, and administrative requirements. The Core allocates the financial resources to individual subprojects and cores. It provides a monthly financial review for project and core leaders. It maintains a log of purchase order requests and receipt of supplies and equipment and for the tracking of expenditure, changes in personnel, and service contracts for the project leaders. It provides expert editorial assistance for preparation of manuscripts and word processing. It coordinates the convening of the internal and external scientific review groups. It handles the travel arrangements for the external review committee members and remuneration for their expenses. It coordinates the weekly research seminar, the monthly meeting of subproject and core leaders and faculty where data are presented and discussed and administrative plans are made and the visits of invited professors. The Core coordinates a biannual meeting on "New insights into Cardiovascular Kidney Disease." This is a 3 day, small group program for opinion leaders in the US and overseas where selected topics from the program project are discussed in depth. The subproject and core leaders present their results and the external review group is invited to participate. This provides the reviewers with an opportunity to become deeply acquainted with the progress of the program and to provide their own comments on detail and substance. The meeting is financed by Division Funds. The Core prepares the reports and summaries which are required by the NIH for administrative review. The Core will support Xin (James) Li, Ph.D. as a biostatistician. He is skilled and experienced in the analysis of gene array data. He will provide statistical guidance and data interpretation to all investigators.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Research Program Projects (P01)
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Special Emphasis Panel (ZHL1-PPG-S (O1))
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Georgetown University
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Pei, Lei; Solis, Glenn; Nguyen, Mien T X et al. (2016) Paracellular epithelial sodium transport maximizes energy efficiency in the kidney. J Clin Invest 126:2509-18
Wang, Zheng; Zeng, Chunyu; Villar, Van Anthony M et al. (2016) Human GRK4γ142V Variant Promotes Angiotensin II Type I Receptor-Mediated Hypertension via Renal Histone Deacetylase Type 1 Inhibition. Hypertension 67:325-34
Jose, Pedro A; Yang, Zhiwei; Zeng, Chunyu et al. (2016) The importance of the gastrorenal axis in the control of body sodium homeostasis. Exp Physiol 101:465-70
Sanada, H; Yoneda, M; Yatabe, J et al. (2016) Common variants of the G protein-coupled receptor type 4 are associated with human essential hypertension and predict the blood pressure response to angiotensin receptor blockade. Pharmacogenomics J 16:3-9
Zhang, Gensheng; Wang, Qiaoling; Zhou, Qin et al. (2016) Protective Effect of Tempol on Acute Kidney Injury Through PI3K/Akt/Nrf2 Signaling Pathway. Kidney Blood Press Res 41:129-38
Jose, Pedro A; Felder, Robin A; Yang, Zhiwei et al. (2016) Gastrorenal Axis. Hypertension 67:1056-63
Li, Lingli; Lai, En Yin; Wellstein, Anton et al. (2016) Differential effects of superoxide and hydrogen peroxide on myogenic signaling, membrane potential, and contractions of mouse renal afferent arterioles. Am J Physiol Renal Physiol 310:F1197-205
Zhang, Yanrong; Jiang, Xiaoliang; Qin, Chuan et al. (2016) Dopamine D2 receptors' effects on renal inflammation are mediated by regulation of PP2A function. Am J Physiol Renal Physiol 310:F128-34
Konkalmatt, Prasad R; Asico, Laureano D; Zhang, Yanrong et al. (2016) Renal rescue of dopamine D2 receptor function reverses renal injury and high blood pressure. JCI Insight 1:
Wang, Renjun; Huang, Qian; Zhou, Rui et al. (2016) Sympathoexcitation in Rats With Chronic Heart Failure Depends on Homeobox D10 and MicroRNA-7b Inhibiting GABBR1 Translation in Paraventricular Nucleus. Circ Heart Fail 9:e002261

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