The mission of the Biostatistics Core is to support and help promote high quality, innovative research in the COAST projects by providing the COAST IV investigators with access to quality data and sophisticated statistical design and analysis. In order to fulfill this mission, the Core staff will collaborate in the design, execution and analysis of the laboratory and clinical research studies and the development and application of new statistical methods as needed by the projects. Core staff will function as collaborative members of research teams. Core staff will be available for advice on statistical issues in the design, conduct, and analysis of studies related to the COAST IV projects. Advice may be related to a project-specific activity or internal review of general issues faced by an investigator. Core staff will also provide on-going support for the COAST IV projects. Core staff will interact with project investigators to identify research questions of interest and the relevant variables within the COAST I, II, III and IV databases. The Biostatistics Core has developed a sophisticated and secure Oracle database system for entering and storing COAST 1,11 and III study data. The Oracle system will continue to be used to manage data on the COAST cohort.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
2P01HL070831-11A1
Application #
8642810
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
2018-06-30
Budget Start
2013-09-26
Budget End
2014-06-30
Support Year
11
Fiscal Year
2013
Total Cost
$235,692
Indirect Cost
$79,086
Name
University of Wisconsin Madison
Department
Type
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Nakagome, Kazuyuki; Bochkov, Yury A; Ashraf, Shamaila et al. (2014) Effects of rhinovirus species on viral replication and cytokine production. J Allergy Clin Immunol 134:332-41
Thomas, Amy O; Lemanske Jr, Robert F; Jackson, Daniel J (2014) Infections and their role in childhood asthma inception. Pediatr Allergy Immunol 25:122-8
Kloepfer, Kirsten M; Lee, Wai Ming; Pappas, Tressa E et al. (2014) Detection of pathogenic bacteria during rhinovirus infection is associated with increased respiratory symptoms and asthma exacerbations. J Allergy Clin Immunol 133:1301-7, 1307.e1-3
Brockman-Schneider, Rebecca A; Pickles, Raymond J; Gern, James E (2014) Effects of vitamin D on airway epithelial cell morphology and rhinovirus replication. PLoS One 9:e86755
Liggett, Stephen B; Bochkov, Yury A; Pappas, Tressa et al. (2014) Genome sequences of rhinovirus a isolates from wisconsin pediatric respiratory studies. Genome Announc 2:
Bousquet, Jean; Gern, James E; Martinez, Fernando D et al. (2014) Birth cohorts in asthma and allergic diseases: report of a NIAID/NHLBI/MeDALL joint workshop. J Allergy Clin Immunol 133:1535-46
Kruger, Stanley J; Fain, Sean B; Johnson, Kevin M et al. (2014) Oxygen-enhanced 3D radial ultrashort echo time magnetic resonance imaging in the healthy human lung. NMR Biomed 27:1535-41
Guilbert, Theresa W; Bacharier, Leonard B; Fitzpatrick, Anne M (2014) Severe asthma in children. J Allergy Clin Immunol Pract 2:489-500
Campbell, Catarina D; Mohajeri, Kiana; Malig, Maika et al. (2014) Whole-genome sequencing of individuals from a founder population identifies candidate genes for asthma. PLoS One 9:e104396
Basta, Holly A; Ashraf, Shamaila; Sgro, Jean-Yves et al. (2014) Modeling of the human rhinovirus C capsid suggests possible causes for antiviral drug resistance. Virology 448:82-90

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