This core unit is located within the administrative offices at the Blood Research Institute, the research arm of the Blood Center of Wisconsin. The BRI includes the offices and laboratories of the research scientists of the institution, but also includes pediatric hematology faculty of the Department of Pediatrics at MCW, and is the location of the Comprehensive Center for Bleeding Disorders. This administrative core will coordinate this multifaceted program and consists of two major components.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Research Program Projects (P01)
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Heart, Lung, and Blood Initial Review Group (HLBP)
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Bloodcenter of Wisconsin, Inc.
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Goodeve, A C; Pavlova, A; Oldenburg, J (2014) Genomics of bleeding disorders. Haemophilia 20 Suppl 4:50-3
Fahs, Scot A; Hille, Matthew T; Shi, Qizhen et al. (2014) A conditional knockout mouse model reveals endothelial cells as the principal and possibly exclusive source of plasma factor VIII. Blood 123:3706-13
de Brasi, C; El-Maarri, O; Perry, D J et al. (2014) Genetic testing in bleeding disorders. Haemophilia 20 Suppl 4:54-8
Laffan, Mike A; Lester, Will; O'Donnell, James S et al. (2014) The diagnosis and management of von Willebrand disease: a United Kingdom Haemophilia Centre Doctors Organization guideline approved by the British Committee for Standards in Haematology. Br J Haematol 167:453-65
Hampshire, Daniel J; Goodeve, Anne C (2014) p.P2063S: a neutral VWF variant masquerading as a mutation. Ann Hematol 93:505-6
Elbatarny, M; Mollah, S; Grabell, J et al. (2014) Normal range of bleeding scores for the ISTH-BAT: adult and pediatric data from the merging project. Haemophilia 20:831-5
Castaman, G; Hillarp, A; Goodeve, A (2014) Laboratory aspects of von Willebrand disease: test repertoire and options for activity assays and genetic analysis. Haemophilia 20 Suppl 4:65-70
Shida, Yasuaki; Rydz, Natalia; Stegner, David et al. (2014) Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and ?2?1-mediated collagen binding in thrombus formation. Blood 124:1799-807
Rusu, Luiza; Andreeva, Alexandra; Visintine, David J et al. (2014) G protein-dependent basal and evoked endothelial cell vWF secretion. Blood 123:442-50
Brott, David A; Katein, Anne; Thomas, Heath et al. (2014) Evaluation of von Willebrand factor and von Willebrand factor propeptide in models of vascular endothelial cell activation, perturbation, and/or injury. Toxicol Pathol 42:672-83

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