Core C: Administrative Core The Administrative Core serves all ofthe projects in this Program and will serve as a cornerstone ofthe cardiovascular community at the University of Washington. The administrative staff coordinates the scientific meetings that permit investigators to share d&ta, troubleshoot technical problems and plan new experiments. The Core manages the cardiovascular seminar series (Cardiovascular Breakfast Club) and the South Lake Union seminaries, weekly forums where trainees present works in progress, and senior scientists from the Seattle region and beyond present formal seminars. Fiscal support for post-award grant management is provided through the Administrative Core, providing Project Leaders with regular budget summaries and analysis of spending trends, as well as assuring financial compliance with federal and institutional financial guidelines. Administrative Core staff work with project leaders to facilitate compliance with animal welfare, embryonic stem cell research oversight and environmental health and safety policies. The Administrative Core is charged with planning the annual PPG retreat, which is attended by one member of the external : advisory board on a rotating basis. At the PPG retreat the project leaders, staff and trainees review progress toward the Program's aims and chart new directions. Finally, the Administrative Core staff assists the Principal Investigator in the day-to-day operations of the program.:

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL094374-05
Application #
8676872
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
2014-06-01
Budget End
2015-05-31
Support Year
5
Fiscal Year
2014
Total Cost
$94,003
Indirect Cost
$31,814
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Hofsteen, Peter; Robitaille, Aaron M; Chapman, Daniel Patrick et al. (2016) Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/β-catenin signaling. Proc Natl Acad Sci U S A 113:1002-7
Ruan, Jia-Ling; Tulloch, Nathaniel L; Razumova, Maria V et al. (2016) Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac Tissue. Circulation 134:1557-1567
Qin, Wan; Roberts, Meredith A; Qi, Xiaoli et al. (2016) Depth-resolved 3D visualization of coronary microvasculature with optical microangiography. Phys Med Biol 61:7536-7550
Pioner, Josè Manuel; Racca, Alice W; Klaiman, Jordan M et al. (2016) Isolation and Mechanical Measurements of Myofibrils from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Stem Cell Reports 6:885-96
Kolwicz Jr, Stephen C; Odom, Guy L; Nowakowski, Sarah G et al. (2016) AAV6-mediated Cardiac-specific Overexpression of Ribonucleotide Reductase Enhances Myocardial Contractility. Mol Ther 24:240-50
Hartman, Matthew E; Dai, Dao-Fu; Laflamme, Michael A (2016) Human pluripotent stem cells: Prospects and challenges as a source of cardiomyocytes for in vitro modeling and cell-based cardiac repair. Adv Drug Deliv Rev 96:3-17
Carson, Daniel; Hnilova, Marketa; Yang, Xiulan et al. (2016) Nanotopography-Induced Structural Anisotropy and Sarcomere Development in Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells. ACS Appl Mater Interfaces 8:21923-32
Thies, R Scott; Murry, Charles E (2015) The advancement of human pluripotent stem cell-derived therapies into the clinic. Development 142:3077-84
Palpant, Nathan J; Hofsteen, Peter; Pabon, Lil et al. (2015) Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and e-cigarettes. PLoS One 10:e0126259
Ruan, Jia-Ling; Tulloch, Nathaniel L; Saiget, Mark et al. (2015) Mechanical Stress Promotes Maturation of Human Myocardium From Pluripotent Stem Cell-Derived Progenitors. Stem Cells 33:2148-57

Showing the most recent 10 out of 75 publications