Core B will provide support for studies involving: (i) H/D-MS/MS analyses (support for Project 1 and 3);(ii) small angle X-ray and neutron scattering measurements and data processing (support for Project 1); (iii) FRET studies (support for Project 3);(iv) Surface plasmon resonance spectroscopy (support for Projects 1 and 3);(v) Microcalorimetry (support for Project 1);(vi) Rapid reaction kinetics analyses ofapoAl lipidation (support for Project 3);(vii) Circular dichroism measurements;(viii) Dynamic/static light scattering analyses of sample dispersity (support for Projects 1, 3);and (ix) Modeling studies (support for Projects 1 and 3).

National Institute of Health (NIH)
Research Program Projects (P01)
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Heart, Lung, and Blood Program Project Review Committee (HLBP)
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Cleveland Clinic Lerner
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Tang, W H Wilson; Wang, Zeneng; Shrestha, Kevin et al. (2015) Intestinal microbiota-dependent phosphatidylcholine metabolites, diastolic dysfunction, and adverse clinical outcomes in chronic systolic heart failure. J Card Fail 21:91-6
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