Core C is designed as the Shared Resources Core. It will provide a number of centralized services to meet the key glycoscience analytical techniques required to achieve the aims set forth in each Project of this PEG. This core is central to the goals ofthe Program, offering several highly innovative technologies created by Program scientists specifically to interrogate glycan structure and function, and ensuring proper execution of a variety of technically-demanding procedures. The Core is divided into 4 components: (1) Glycoanalytic Component;(2) Adhesion Assay Component;(3) Ex Vivo Glycan Engineering Component;and (4) In Vitro Glycosyltransferase and Glycosidase Component. This core realizes the Program's intent to sustain an experimentally integrated effort, and ensures that data derived from glycoscience-specialized activities will be uniformly reproducible among all the Projects.
Core C is designed as the Shared Resources Core. It will provide a number of centralized services to meet the key glycoscience analytical techniques required to achieve the aims set forth in each Project of this PEG.
|Liu, Zhi-Jian; Hoffmeister, Karin M; Hu, Zhongbo et al. (2014) Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan. Blood 123:3381-9|
|Liu, Gang; Neelamegham, Sriram (2014) A computational framework for the automated construction of glycosylation reaction networks. PLoS One 9:e100939|
|Nasirikenari, Mehrab; Veillon, Lucas; Collins, Christine C et al. (2014) Remodeling of marrow hematopoietic stem and progenitor cells by non-self ST6Gal-1 sialyltransferase. J Biol Chem 289:7178-89|
|Dauber, Andrew; Ercan, Altan; Lee, Jack et al. (2014) Congenital disorder of fucosylation type 2c (LADII) presenting with short stature and developmental delay with minimal adhesion defect. Hum Mol Genet 23:2880-7|
|Lee, Melissa M; Nasirikenari, Mehrab; Manhardt, Charles T et al. (2014) Platelets support extracellular sialylation by supplying the sugar donor substrate. J Biol Chem 289:8742-8|
|Ashline, David J; Hanneman, Andrew J S; Zhang, Hailong et al. (2014) Structural documentation of glycan epitopes: sequential mass spectrometry and spectral matching. J Am Soc Mass Spectrom 25:444-53|
|Batal, Ibrahim; Azzi, Jamil; Mounayar, Marwan et al. (2014) The mechanisms of up-regulation of dendritic cell activity by oxidative stress. J Leukoc Biol 96:283-93|
|Silvescu, Cristina I; Sackstein, Robert (2014) G-CSF induces membrane expression of a myeloperoxidase glycovariant that operates as an E-selectin ligand on human myeloid cells. Proc Natl Acad Sci U S A 111:10696-701|
|Dykstra, Brad; Bystrykh, Leonid V (2014) No monkeying around: clonal tracking of stem cells and progenitors in the macaque. Cell Stem Cell 14:419-20|
|Cabral, M Guadalupe; Silva, Zelia; Ligeiro, Dario et al. (2013) The phagocytic capacity and immunological potency of human dendritic cells is improved by *2,6-sialic acid deficiency. Immunology 138:235-45|
Showing the most recent 10 out of 19 publications