Glycosciences Skills Development is a key component of the Lung Inflammatory Disease Program of Excellence in Glycoscience (LID-PEG). Four postdoctoral fellows will be designated as Skills Development Trainees with terms of 3-4 years. At any time, one Skills Development Trainee will be associated with (and supported by) each Project. Training will consist of three components: (1) Site-specific courses in glycobiology - With the assumption that glycobiology training is often modest at the doctoral and pre-doctoral levels, Skills Development Trainees will enroll in site-specific courses in the fundamentals of glycobiology. These opportunities will include """"""""Essentials of Glycobiology"""""""" (at UCSD for trainees at Scripps), """"""""Advanced Topics in Glycobiology"""""""" (at University of Georgia for trainees at the CCRC) and a newly created graduate-level course on Glycobiology directed by Dr. Schnaar (for trainees at Johns Hopkins). (2) Annual Skills Development Retreats - Each year all Skills Development Trainees will travel to one of the three Program sites (in rotation) for hands-on training. This will provide specialized experiences in glycoconjugate purification, analysis, chemistry and function. In addition, it will provide opportunities for every trainee to visit and network with glycoscientists at three of the major glycobiology centers in the US. (3) Enrichment and networking opportunities. Each site provides exanded opportunities for informal glycoscience training through specialized glycobiology seminar series and local or regional glycobiology interest groups. In addition, all trainees will attend the annual Society for Glycobiology meeting, the Glycobiology Gordon Conference, or other international or specialized meetings in the glycosciences.
Building an ongoing infrastructure capable of applying glycosciences to discovery and therapeutic development relevant to the mission of the NHLBI will require the training of the next generation of leaders in the field.
|O'Sullivan, Jeremy A; Bochner, Bruce S (2017) Eosinophils and eosinophil-associated diseases: An update. J Allergy Clin Immunol :|
|Yu, Huifeng; Gonzalez-Gil, Anabel; Wei, Yadong et al. (2017) Siglec-8 and Siglec-9 binding specificities and endogenous airway ligand distributions and properties. Glycobiology 27:657-668|
|O'Sullivan, Jeremy A; Carroll, Daniela J; Cao, Yun et al. (2017) Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and malignant mast cells. J Allergy Clin Immunol :|
|Carroll, Daniela J; O'Sullivan, Jeremy A; Nix, David B et al. (2017) Sialic acid-binding immunoglobulin-like lectin 8 (Siglec-8) is an activating receptor mediating ?2-integrin-dependent function in human eosinophils. J Allergy Clin Immunol :|
|Guo, Hongbo; de Vries, Erik; McBride, Ryan et al. (2017) Highly Pathogenic Influenza A(H5Nx) Viruses with Altered H5 Receptor-Binding Specificity. Emerg Infect Dis 23:220-231|
|Lou, Hongfei; Lu, Jingning; Choi, Eun Byul et al. (2017) Expression of IL-22 in the Skin Causes Th2-Biased Immunity, Epidermal Barrier Dysfunction, and Pruritus via Stimulating Epithelial Th2 Cytokines and the GRP Pathway. J Immunol 198:2543-2555|
|Peng, Wenjie; Paulson, James C (2017) CD22 Ligands on a Natural N-Glycan Scaffold Efficiently Deliver Toxins to B-Lymphoma Cells. J Am Chem Soc 139:12450-12458|
|Schnaar, Ronald L; Lee, Yuan C (2017) Discoveries of the structures of sialic acid and CMP-sialic acid (1957-1960): A letter from Saul Roseman. Glycobiology :|
|Wu, Nicholas C; Xie, Jia; Zheng, Tianqing et al. (2017) Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin. Cell Host Microbe 21:742-753.e8|
|Schleimer, Robert P; Schnaar, Ronald L; Bochner, Bruce S (2016) Regulation of airway inflammation by Siglec-8 and Siglec-9 sialoglycan ligand expression. Curr Opin Allergy Clin Immunol 16:24-30|
Showing the most recent 10 out of 65 publications