Core A will provide logistics support for all other projects and cores. Regular group meetings will be coordinated through Core A. Many of the organizational elements have come into existence during the past year preparing for submission of the proposal, including regular group meetings where off-site members have joined via Skype, regularly scheduled face-to-face meetings coordinated with scientific conferences, and exchange of lab personnel. The Administrative Core will establish and maintain an interactive web-based platform to support communications among members via email, GoogleDocs, and Skype video conferencing. Interactions with the internal and external advisory boards will be coordinated through Core A. The Core will facilitate preparation and submission of abstracts and manuscripts, ensure timely submission of progress reports to NIH, and provide budgetary oversight for project expenditures. Purchasing, sample receiving and archiving, publications, and travel will be coordinated through Core A. This Core will monitor progress of each Project and Core, and will coordinate studies among investigators. The Core will manage the database, which will allow tracking and consolidation of all experimental data linked to each animal.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Research Program Projects (P01)
Project #
Application #
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Cedars-Sinai Medical Center
Los Angeles
United States
Zip Code
Lindsey, Merry L; Bolli, Roberto; Canty Jr, John M et al. (2018) Guidelines for experimental models of myocardial ischemia and infarction. Am J Physiol Heart Circ Physiol 314:H812-H838
Coronado, Michael; Fajardo, Giovanni; Nguyen, Kim et al. (2018) Physiological Mitochondrial Fragmentation Is a Normal Cardiac Adaptation to Increased Energy Demand. Circ Res 122:282-295
Stastna, Miroslava; Thomas, Amandine; Germano, Juliana et al. (2018) Dynamic Proteomic and miRNA Analysis of Polysomes from Isolated Mouse Heart After Langendorff Perfusion. J Vis Exp :
Chung, Heaseung Sophia; Murray, Christopher I; Van Eyk, Jennifer E (2018) A Proteomics Workflow for Dual Labeling Biotin Switch Assay to Detect and Quantify Protein S-Nitroylation. Methods Mol Biol 1747:89-101
Crupi, Annunziata N; Nunnelee, Jordan S; Taylor, David J et al. (2018) Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging. Aging (Albany NY) 10:3327-3352
Delbridge, Lea M D; Mellor, Kimberley M; Taylor, David J et al. (2017) Myocardial stress and autophagy: mechanisms and potential therapies. Nat Rev Cardiol 14:412-425
Chung, Heaseung Sophia; Kim, Grace E; Holewinski, Ronald J et al. (2017) Transient receptor potential channel 6 regulates abnormal cardiac S-nitrosylation in Duchenne muscular dystrophy. Proc Natl Acad Sci U S A 114:E10763-E10771
Gottlieb, Roberta A; Thomas, Amandine (2017) Mitophagy and Mitochondrial Quality Control Mechanisms in the Heart. Curr Pathobiol Rep 5:161-169
Gottlieb, Roberta A (2017) Delivering Instant Heat: Shocking the Heart. J Am Coll Cardiol 70:1493-1495
Giricz, Zoltán; Koncsos, Gábor; Rajtík, Tomáš et al. (2017) Hypercholesterolemia downregulates autophagy in the rat heart. Lipids Health Dis 16:60

Showing the most recent 10 out of 41 publications