The Administrative and Biostatistics Core (Core A) will provide administrative support for all ofthe Projects and other Cores in this translational Program Project Grant (tPPG). It will coordinate the scientific objectives and interactions of all component units ofthe Program, provide oversight to ensure fiscal responsibility, and provide a structure that optimizes interactions with the institution as well as with NIH. These tasks will be accomplished by an experienced administrative management team with a track record of working together and with adequate physical, infrastructure, and computing resources. The specific tasks this Core will be as follows: 1. Schedule regular meetings of Project and Core unit leaders to monitor scientific progress, productivity, and synergy as well as to troubleshoot emerging concerns regarding administrative issues or budget allocations. 2. Provide statistical and data processing support. 3. Optimize utilization of shared supplies and services while maintaining quality and economies of scale. 4. Coordinate annual meetings ofthe Internal and External Advisory Boards to provide scientific input to Program investigators. 5. Manage all financial aspects of the grant, including expenditures, fiscal integrity, and budget allocations. 6. Work with the institution and the NIH to ensure effective interactions and communication. 7. Take responsibility for annual progress reports to NIH. 8. Arrange for and provide reimbursement to key investigators for travel to scientific meetings. 9. Provide support to investigators, including secretarial supplies and assistance, personnel management, and generation of documents, including manuscripts. 10. Manage any necessary changes in key personnel or in Program leadership.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Research Program Projects (P01)
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Study Section
Special Emphasis Panel (ZHL1-CSR-Q (M1))
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University of Alabama Birmingham
United States
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Huang, Wen-Tan; Akhter, Hasina; Jiang, Chunsun et al. (2015) Plasminogen activator inhibitor 1, fibroblast apoptosis resistance, and aging-related susceptibility to lung fibrosis. Exp Gerontol 61:62-75
Thannickal, Victor J; Zhou, Yong; Gaggar, Amit et al. (2014) Fibrosis: ultimate and proximate causes. J Clin Invest 124:4673-7
Xie, Na; Cui, Huachun; Banerjee, Sami et al. (2014) miR-27a regulates inflammatory response of macrophages by targeting IL-10. J Immunol 193:327-34
Desai, Leena P; Zhou, Yong; Estrada, Aida V et al. (2014) Negative regulation of NADPH oxidase 4 by hydrogen peroxide-inducible clone 5 (Hic-5) protein. J Biol Chem 289:18270-8
Blackwell, Timothy S; Tager, Andrew M; Borok, Zea et al. (2014) Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report. Am J Respir Crit Care Med 189:214-22
Hu, Meng; Che, Pulin; Han, Xiaosi et al. (2014) Therapeutic targeting of SRC kinase in myofibroblast differentiation and pulmonary fibrosis. J Pharmacol Exp Ther 351:87-95
Bai, Guangxing; Hock, Thomas D; Logsdon, Naomi et al. (2014) A far-upstream AP-1/Smad binding box regulates human NOX4 promoter activation by transforming growth factor-?. Gene 540:62-7
Hecker, Louise; Logsdon, Naomi J; Kurundkar, Deepali et al. (2014) Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance. Sci Transl Med 6:231ra47
Cui, Huachun; Xie, Na; Tan, Zheng et al. (2014) The human long noncoding RNA lnc-IL7R regulates the inflammatory response. Eur J Immunol 44:2085-95
Karki, Suman; Surolia, Ranu; Hock, Thomas David et al. (2014) Wilms' tumor 1 (Wt1) regulates pleural mesothelial cell plasticity and transition into myofibroblasts in idiopathic pulmonary fibrosis. FASEB J 28:1122-31

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