The Administrative and Biostatistics Core (Core A) will provide administrative support for all ofthe Projects and other Cores in this translational Program Project Grant (tPPG). It will coordinate the scientific objectives and interactions of all component units ofthe Program, provide oversight to ensure fiscal responsibility, and provide a structure that optimizes interactions with the institution as well as with NIH. These tasks will be accomplished by an experienced administrative management team with a track record of working together and with adequate physical, infrastructure, and computing resources. The specific tasks this Core will be as follows: 1. Schedule regular meetings of Project and Core unit leaders to monitor scientific progress, productivity, and synergy as well as to troubleshoot emerging concerns regarding administrative issues or budget allocations. 2. Provide statistical and data processing support. 3. Optimize utilization of shared supplies and services while maintaining quality and economies of scale. 4. Coordinate annual meetings ofthe Internal and External Advisory Boards to provide scientific input to Program investigators. 5. Manage all financial aspects of the grant, including expenditures, fiscal integrity, and budget allocations. 6. Work with the institution and the NIH to ensure effective interactions and communication. 7. Take responsibility for annual progress reports to NIH. 8. Arrange for and provide reimbursement to key investigators for travel to scientific meetings. 9. Provide support to investigators, including secretarial supplies and assistance, personnel management, and generation of documents, including manuscripts. 10. Manage any necessary changes in key personnel or in Program leadership.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL114470-02
Application #
8735181
Study Section
Special Emphasis Panel (ZHL1)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
2
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Type
DUNS #
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Bernard, Karen; Logsdon, Naomi J; Miguel, Veronica et al. (2017) NADPH Oxidase 4 (Nox4) Suppresses Mitochondrial Biogenesis and Bioenergetics in Lung Fibroblasts via a Nuclear Factor Erythroid-derived 2-like 2 (Nrf2)-dependent Pathway. J Biol Chem 292:3029-3038
Li, Fu Jun; Surolia, Ranu; Li, Huashi et al. (2017) Autoimmunity to Vimentin Is Associated with Outcomes of Patients with Idiopathic Pulmonary Fibrosis. J Immunol 199:1596-1605
Ge, Jing; Cui, Huachun; Xie, Na et al. (2017) Glutaminolysis Promotes Collagen Translation and Stability via ?-ketoglutarate Mediated mTOR Activation and Proline Hydroxylation. Am J Respir Cell Mol Biol :
Cui, Huachun; Ge, Jing; Xie, Na et al. (2017) miR-34a promotes fibrosis in aged lungs by inducing alveolarepithelial dysfunctions. Am J Physiol Lung Cell Mol Physiol 312:L415-L424
Hough, K P; Chanda, D; Duncan, S R et al. (2017) Exosomes in immunoregulation of chronic lung diseases. Allergy 72:534-544
Sanders, Yan Y; Liu, Hui; Scruggs, Anne M et al. (2017) Epigenetic Regulation of Caveolin-1 Gene Expression in Lung Fibroblasts. Am J Respir Cell Mol Biol 56:50-61
Cui, Huachun; Ge, Jing; Xie, Na et al. (2017) miR-34a Inhibits Lung Fibrosis by Inducing Lung Fibroblast Senescence. Am J Respir Cell Mol Biol 56:168-178
de Andrade, Joao A; Luckhardt, Tracy (2017) What Is in a Pattern? That Which We Call Idiopathic Pulmonary Fibrosis by Any Other Pattern Would Behave Alike! Am J Respir Crit Care Med 195:10-12
Xie, Na; Cui, Huachun; Ge, Jing et al. (2017) Metabolic characterization and RNA profiling reveal glycolytic dependence of profibrotic phenotype of alveolar macrophages in lung fibrosis. Am J Physiol Lung Cell Mol Physiol 313:L834-L844
Surolia, Ranu; Li, Fu Jun; Wang, Zheng et al. (2017) 3D pulmospheres serve as a personalized and predictive multicellular model for assessment of antifibrotic drugs. JCI Insight 2:e91377

Showing the most recent 10 out of 60 publications